Reactome | Negative regulation by 'KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane]' Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

Schema > RegulationReference > Entries

created	[InstanceEdit:9669882] Rothfels, Karen, 2019-12-03
dbId	9669883
displayName	Negative regulation by 'KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane]' Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours
literatureReference	[LiteratureReference:9669094] Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours [LiteratureReference:9669059] Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412
regulatedBy	[NegativeRegulation:9669884] Negative regulation by 'KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane]'
schemaClass	RegulationReference

(regulationReference)

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