Reactome | Negative regulation by 'LEP:p-LEPR:p-JAK2:SOCS3 [plasma membrane]' SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

Schema > RegulationReference > Entries

created	[InstanceEdit:9641190] Wu, G, 2019-04-04
dbId	9641585
displayName	Negative regulation by 'LEP:p-LEPR:p-JAK2:SOCS3 [plasma membrane]' SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985
literatureReference	[LiteratureReference:2672304] SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985 [LiteratureReference:2672297] Mechanism of attenuation of leptin signaling under chronic ligand stimulation [LiteratureReference:4420064] The role of SOCS-3 in leptin signaling and leptin resistance
regulatedBy	[NegativeRegulation:R-HSA-4420081] Negative regulation by 'LEP:p-LEPR:p-JAK2:SOCS3 [plasma membrane]'
schemaClass	RegulationReference

(regulationReference)

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