Reactome | Positive regulation by 'CABLES1 [nucleoplasm]'

Schema > PositiveRegulation > Entries

created	[InstanceEdit:9605538] Orlic-Milacic, Marija, 2018-04-13
dbId	9605537
displayName	Positive regulation by 'CABLES1 [nucleoplasm]'
modified	[InstanceEdit:9608021] Wu, G, 2018-05-08
regulatedEntity	[Reaction:R-HSA-174164] Phosphorylation of Cyclin A:Cdk2 at Tyr 15 - Homo sapiens
regulator	[EntityWithAccessionedSequence:R-HSA-1013870] CABLES1 [nucleoplasm]
schemaClass	PositiveRegulation

(regulation)	[RegulationReference:9642766] Positive regulation by 'CABLES1 [nucleoplasm]' Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers
(regulatedBy)	[Reaction:R-HSA-174164] Phosphorylation of Cyclin A:Cdk2 at Tyr 15

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