In the absence of Hh signal, GLI1 is degraded by the proteas...
| created | [InstanceEdit:5610674] Rothfels, Karen, 2014-07-22 |
| dbId | 5610673 |
| displayName | In the absence of Hh signal, GLI1 is degraded by the proteas... |
| schemaClass | Summation |
| text | In the absence of Hh signal, GLI1 is degraded by the proteasome. Degradation depends on GLI1 ubiquitination by SCF(beta-TrCP) and by the E3 ligase ITCH (Huntzicker et al, 2006; di Marcotullio et al, 2006, 2011). |
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