intrinsic apoptotic signaling pathway

accession 0097193
created [InstanceEdit:2133145] Weiser, JD
databaseName GO
dbId 2133500
definition The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).
displayName intrinsic apoptotic signaling pathway
modified [InstanceEdit:9676538] Cook, Justin, 2020-02-17
name intrinsic apoptotic signaling pathway
referenceDatabase [ReferenceDatabase:1] GO
schemaClass GO_BiologicalProcess
url https://www.ebi.ac.uk/QuickGO/term/GO:0097193
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