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C3b [extracellular region]
Stable Identifier
R-SSC-166832
Type
Complex
Species
Sus scrofa
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Complement cascade (Sus scrofa)
Activation of C3 and C5 (Sus scrofa)
Activation of C5 (Sus scrofa)
C5 convertases [plasma membrane] (Sus scrofa)
C3b:Bb:C3b:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
C4b:C2a:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cleavage of C3 by C3 convertases (Sus scrofa)
C3 convertases [plasma membrane] (Sus scrofa)
C4b:C2a:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Formation of classic pathway C5 convertase (Sus scrofa)
C4b:C2a:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Initial triggering of complement (Sus scrofa)
Alternative complement activation (Sus scrofa)
C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
C3b binds to cell surface (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor B binds to surface-associated C3b (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:CFB [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor D cleaves C3b-bound Factor B (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:CFB [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Formation of alternative pathway C5 convertase (Sus scrofa)
C3b:Bb:C3b:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Properdin stabilizes C3b:Bb bound to cell surfaces (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Regulation of Complement cascade (Sus scrofa)
C3 convertases spontaneously dissociate (Sus scrofa)
C3 convertases [plasma membrane] (Sus scrofa)
C4b:C2a:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CD46 binds C3b (Sus scrofa)
CD46:Cell surface:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CD55 (DAF) binds C3bBb, C4bC2a (Sus scrofa)
C4bC2a, C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CD55:C3 convertase complexes [plasma membrane] (Sus scrofa)
CD55:C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Sus scrofa)
CD55:C3 convertase complexes [plasma membrane] (Sus scrofa)
CD55:C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CD55:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CR1 binds C3bBb/C4bC2a (Sus scrofa)
C4bC2a, C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CR1:C3bBb, C4bC2a complexes [plasma membrane] (Sus scrofa)
CR1:C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Complement factor I binds to MCP, CR1:C4b, C3b (Sus scrofa)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Sus scrofa)
CD46:Cell surface:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CR1:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Sus scrofa)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Sus scrofa)
CD46:Cell surface:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CR1:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Complement factor I binds to extracellular Factor H:C3b (Sus scrofa)
CFH:C3b [extracellular region] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CFI:CFH:C3b [extracellular region] (Sus scrofa)
CFH:C3b [extracellular region] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Complement factor I binds to membrane-associated Factor H:C3b (Sus scrofa)
CFI:CFH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:FH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:FH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Displacement of C2a/Bb by CR1 (Sus scrofa)
CR1:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CR1:C3bBb, C4bC2a complexes [plasma membrane] (Sus scrofa)
CR1:C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor H binds to C3b (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CFH:C3b [extracellular region] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor H binds to C3bBb (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:CFH, CFHR3:C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor H binds to membrane-associated C3b (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:FH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor H displaces Bb (Sus scrofa)
Cell surface:CFH, CFHR3:C3bBb [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Cell surface:FH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor I inactivates Factor H-boundC3b (Sus scrofa)
CFI:CFH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:FH,FHR3:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor I inactivates MCP/CR1-bound C4b/C3b (Sus scrofa)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Sus scrofa)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Sus scrofa)
CD46:Cell surface:C3b [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
CR1:C3b [plasma membrane] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
Factor I inactivates plasma Factor H-bound C3b (Sus scrofa)
CFI:CFH:C3b [extracellular region] (Sus scrofa)
CFH:C3b [extracellular region] (Sus scrofa)
C3b [extracellular region] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
C3 [extracellular region]
(Sus scrofa)
C3 [extracellular region]
(Sus scrofa)
Participates
as an output of
C3 convertases spontaneously dissociate (Sus scrofa)
Cleavage of C3 by C3 convertases (Sus scrofa)
C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Sus scrofa)
as a component of
CD55:C3b [plasma membrane] (Sus scrofa)
CFH:C3b [extracellular region] (Sus scrofa)
CR1:C3b [plasma membrane] (Sus scrofa)
C3b:Bb:C3b:Properdin [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb:Properdin [plasma membrane] (Sus scrofa)
Cell surface:C3b:Bb [plasma membrane] (Sus scrofa)
Cell surface:C3b [plasma membrane] (Sus scrofa)
as an input of
Factor H binds to C3b (Sus scrofa)
C3b binds to cell surface (Sus scrofa)
Inferred From
C3b [extracellular region]
(Homo sapiens)
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