Reactome | activated thrombin (factor IIa) [extracellular region]

activated thrombin (factor IIa) [extracellular region]

Stable Identifier

R-SSC-156786

Type

Complex

Species

Sus scrofa

Compartment

extracellular region

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 6 Ca2+ [extracellular region]
F2 [extracellular region] (Sus scrofa)
F2 [extracellular region] (Sus scrofa)

Participates

as an input of

Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Sus scrofa)
activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Sus scrofa)
Factor IIa inhibitors (compounds) binds IIa (Sus scrofa)
Factor IIa inhibitors (peptide) bind IIa (Sus scrofa)
activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Sus scrofa)
Proteinase-activated receptors can bind thrombin (Sus scrofa)

as an output of

prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) (Sus scrofa)
prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Sus scrofa)

as a component of

thrombin:cleaved SERPINC1 [extracellular region] (Sus scrofa)
activated thrombin (factor IIa):SERPIND1 [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (compounds):IIa [extracellular region] (Sus scrofa)
Thrombin:Proteinase-activated receptors [plasma membrane] (Sus scrofa)

as a member of

Activated thrombin, (ELANE) [extracellular region] (Sus scrofa)

Inferred From

activated thrombin (factor IIa) [extracellular region] (Homo sapiens)

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