Reactome | MCM4 [nucleoplasm]

MCM4 [nucleoplasm]

Stable Identifier

R-SCE-68549

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

P30665

Locations in the PathwayBrowser for interactor UniProt:P32354

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External Reference Information

External Reference

UniProt:P30665 MCM4

Gene Names

MCM4, CDC54, HCD21, YPR019W, YP9531.13

Chain

chain:1-933

Reference Genes

BioGPS Gene:856130 MCM4

KEGG:sce:YPR019W MCM4

Monarch:856130 MCM4

NCBI Gene:856130 MCM4

UCSC:P30665 MCM4

Reference Transcript

RefSeq:NM_001184116.1 MCM4

Other Identifiers

856130

GO:0000166

GO:0000727

GO:0003674

GO:0003677

GO:0003678

GO:0003688

GO:0003697

GO:0004386

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005654

GO:0005656

GO:0005737

GO:0006260

GO:0006267

GO:0006268

GO:0006270

GO:0006271

GO:0006279

GO:0006281

GO:0006310

GO:0008150

GO:0008270

GO:0009378

GO:0016787

GO:0016887

GO:0017116

GO:0031261

GO:0031298

GO:0033260

GO:0034214

GO:0042555

GO:0043138

GO:0043167

GO:0043596

GO:0071162

GO:0097373

GO:0140657

GO:1902975

Participates

as an input of

MCM4, MCM6 and MCM7 form a heterotrimer (Saccharomyces cerevisiae)

as a component of

MCM4:MCM6:MCM7 [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

yMcm4 [nucleoplasm]

Inferred From

MCM4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_015344.1

ENSEMBL

YPR019W, YPR019W_mRNA, YPR019W

PRO

P30665

PDB

8P63, 7PMK, 5U8S, 3JC7, 6SKO, 8RIF, 3JC6, 7V3U, 7P5Z, 7QHS, 5V8F, 7Z13, 8RIG, 8P5E, 9E2W, 7PMN, 9BCX, 6PTO, 9GJP, 9GM5, 8B9B, 6HV9, 8B9C, 6U0M, 8XGC, 6WGI, 3JA8, 7PT6, 7P30, 8KG8, 6RQC, 5U8T, 8W7M, 6WGF, 5BK4, 7V3V, 3JC5, 6SKL, 6PTJ, 9E2X, 9E2Y, 5XF8, 6F0L, 8W7S, 6PTN, 8P62, 8KG9, 9GJW, 8B9A, 7W8G, 8KG6, 7PT7, 6WGG, 6EYC

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29469 MCM2	2	MCM2 [nucleoplasm] (R-SCE-68557) yMcm2 [nucleoplasm] (R-SCE-169497)	0.944	16
UniProt:P53091 MCM6	2	MCM6 [nucleoplasm] (R-SCE-68553) yMcm6 [nucleoplasm] (R-SCE-169504)	0.813	8
UniProt:Q08032	1	CDC45 [nucleoplasm] (R-SCE-68563)	0.793	8
UniProt:Q01454 CTF4			0.788	6
UniProt:P38132 MCM7	2	MCM7 [nucleoplasm] (R-SCE-68555) yMcm7 [nucleoplasm] (R-SCE-169505)	0.759	4
UniProt:Q03406	1	SLD5 [nucleoplasm] (R-SCE-176963)	0.758	8
UniProt:Q12488	1	PSF1 [nucleoplasm] (R-SCE-176955)	0.744	6
UniProt:P24279 MCM3	2	MCM3 [nucleoplasm] (R-SCE-68546) yMcm3 [nucleoplasm] (R-SCE-169513)	0.725	4
UniProt:P29496 MCM5	2	MCM5 [nucleoplasm] (R-SCE-68551) yMcm5 [nucleoplasm] (R-SCE-169511)	0.725	8
UniProt:P32354	1	MCM10 [nucleoplasm] (R-SCE-68403)	0.669	4
UniProt:P13382	1	POLA1 [nucleoplasm] (R-SCE-68487)	0.643	3
UniProt:P47112 TAH11	1	yCDT1 [nucleoplasm] (R-SCE-9749306)	0.638	4
UniProt:P09119 CDC6	4	phospho-p-CDC6 [cytosol] (R-SCE-68583) phospho-p-CDC6 [nucleoplasm] (R-SCE-5661317) yCDC6 [nucleoplasm] (R-SCE-9749328) CDC6 [nucleoplasm] (R-SCE-68542)	0.606	3
UniProt:Q9BTE3-2 MCMBP			0.556	3
UniProt:P40359	1	PSF2 [nucleoplasm] (R-SCE-176975)	0.527	2
UniProt:Q04636	1	POB3 [nucleoplasm] (R-SCE-65105)	0.527	2
UniProt:Q12146	1	PSF3 [nucleoplasm] (R-SCE-5688046)	0.527	2
UniProt:Q04659	1	CSM3 [nucleoplasm] (R-SCE-5684983)	0.527	3
UniProt:Q12306	5	SMT3 [nucleoplasm] (R-SCE-2990831) SMT3 [nucleoplasm] (R-SCE-877304) SMT3 [nucleoplasm] (R-SCE-3730616) SMT3 [nucleoplasm] (R-SCE-3730622) SMT3 [cytosol] (R-SCE-4656941)	0.524	2

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