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S-Farn-proKRAS [endoplasmic reticulum membrane]
Stable Identifier
R-RNO-9647925
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum membrane
Synonyms
P08644
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS processing (Rattus norvegicus)
RCE1 cleaves S-Farn proRAS proteins (Rattus norvegicus)
S-Farn-proRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
S-Farn-proKRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
pro-RAS proteins are farnesylated (Rattus norvegicus)
S-Farn-proRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
S-Farn-proKRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P08644 Kras
Gene Names
Kras, Kras2
Chain
chain:1-186, initiator methionine:, chain:2-186, propeptide:187-189
Reference Genes
BioGPS Gene:24525 Kras
ENSEMBL:ENSRNOG00055009514 Kras
ENSEMBL:ENSRNOG00060008032 Kras
ENSEMBL:ENSRNOG00065005903 Kras
KEGG Gene (Rattus norvegicus):24525 Kras
Monarch:24525 Kras
NCBI Gene:24525 Kras
UCSC:P08644 Kras
Reference Transcript
RefSeq:NM_031515.3 Kras
RefSeq:XM_017592443.1 Kras
RefSeq:XM_008763354.2 Kras
RefSeq:XM_017592442.1 Kras
Participates
as a member of
S-Farn-proRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
Other forms of this molecule
phospho-p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane]
KRAS [plasma membrane]
S-Farn-Me KRAS4A [plasma membrane]
S-Farn-Me KRAS4B [cytosol]
phospho-pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane]
phospho-pS181-S-Farn-Me KRAS4B [plasma membrane]
S-Farn-Me PalmS KRAS4A [Golgi membrane]
S-Farn-Me KRAS [endoplasmic reticulum membrane]
S-Farn-Me KRAS4B [endoplasmic reticulum membrane]
S-Farn-KRAS [endoplasmic reticulum membrane]
S-Farn KRAS4B [endoplasmic reticulum membrane]
S-Farn proKRAS4B [endoplasmic reticulum membrane]
proKRAS [cytosol]
pro-KRAS4A [cytosol]
Kras [plasma membrane]
S-Farn-Me-PalmS KRAS4A [plasma membrane]
S-Farn-Me KRAS4B [plasma membrane]
Inferred From
S-Farn proKRAS4A [endoplasmic reticulum membrane]
(Homo sapiens)
S-Farn-proKRAS [endoplasmic reticulum membrane]
(Homo sapiens)
Modified Residues
Name
S-farnesyl-L-cysteine at 186 (in Homo sapiens)
Coordinate
186
PsiMod Name
S-farnesyl-L-cysteine [MOD:00111]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine.
Cross References
RefSeq
XP_017447931.1
,
XP_008761576.1
,
XP_017447932.1
,
NP_113703.1
PRO
P08644
RGD
2981
PDB
1N4S
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