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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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S-Farn-Me-PalmS KRAS4A [plasma membrane]
Stable Identifier
R-RNO-9647915
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
P08644
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
NCAM signaling for neurite out-growth (Rattus norvegicus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
Tie2 Signaling (Rattus norvegicus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Downstream signaling events of B Cell Receptor (BCR) (Rattus norvegicus)
Activation of RAS in B cells (Rattus norvegicus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
FLT3 Signaling (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by CSF3 (G-CSF) (Rattus norvegicus)
p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CD209 (DC-SIGN) signaling (Rattus norvegicus)
PAK phosphorylates p21 RAF1 on S338 (Rattus norvegicus)
p21 RAS:GTP:RAF1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAF1 binds p21 RAS:GTP (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:RAF1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
SFKs phosphorylates RAF1 on Y340,Y341 (Rattus norvegicus)
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
DAP12 interactions (Rattus norvegicus)
DAP12 signaling (Rattus norvegicus)
SOS mediated nucleotide exchange of RAS (SHC) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
FCERI mediated MAPK activation (Rattus norvegicus)
SOS mediated nucleotide exchange of RAS (SHC) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
Intrinsic nucleotide exchange on RAS (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
MAP2K and MAPK activation (Rattus norvegicus)
Dissociation of RAS:RAF complex (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Dual mechanism MAPK inhibitors bind MAPKs (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
MAP2Ks and MAPKs bind to the activated RAF complex (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
MAP2Ks phosphorylate MAPKs (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAF phosphorylates MAP2K dimer (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Negative regulation of MAPK pathway (Rattus norvegicus)
BRAP autoubiquitinates (Rattus norvegicus)
p21 RAS:GTP:BRAP [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
BRAP binds RAS:GTP (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:BRAP [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
PEBP1 binds activated RAF1 (Rattus norvegicus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
PP2A dephosphorylates RAF1 (Rattus norvegicus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
PP5 dephosphorylates RAF1 S338 (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAF activation (Rattus norvegicus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Phosphorylation of RAF (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Raf dimer inhibitors bind RAF heterodimers (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS processing (Rattus norvegicus)
RAS proteins are depalmitoylated (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A, HRAS, NRAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
mature RAS proteins translocate to plasma membrane (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A, HRAS, NRAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
mature p21 RAS binds GDP (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS:GTP binds PI3K (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:PI3K [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Regulation of RAS by GAPs (Rattus norvegicus)
RAS GAPs bind RAS:GTP (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS GAPs stimulate RAS GTPase activity (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (q) signalling events (Rattus norvegicus)
Gastrin-CREB signalling pathway via PKC and MAPK (Rattus norvegicus)
EGFR Transactivation by Gastrin (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by Non-Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PTK6 (Rattus norvegicus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Rattus norvegicus)
RASA1 binds RAS:GTP (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:RASA1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RASA1 stimulates RAS GTPase activity (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:RASA1 [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
Estrogen-stimulated signaling through PRKCZ (Rattus norvegicus)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Rattus norvegicus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
PRKCZ recruits RAS in response to estrogen stimulation (Rattus norvegicus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Rattus norvegicus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
GRB2 events in EGFR signaling (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
SHC1 events in EGFR signaling (Rattus norvegicus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by ERBB2 (Rattus norvegicus)
GRB2 events in ERBB2 signaling (Rattus norvegicus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by ERBB4 (Rattus norvegicus)
SHC1 events in ERBB4 signaling (Rattus norvegicus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Downstream signaling of activated FGFR1 (Rattus norvegicus)
FRS-mediated FGFR1 signaling (Rattus norvegicus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
SHC-mediated cascade:FGFR1 (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by FGFR2 (Rattus norvegicus)
Downstream signaling of activated FGFR2 (Rattus norvegicus)
FRS-mediated FGFR2 signaling (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
SHC-mediated cascade:FGFR2 (Rattus norvegicus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by FGFR3 (Rattus norvegicus)
Downstream signaling of activated FGFR3 (Rattus norvegicus)
FRS-mediated FGFR3 signaling (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
SHC-mediated cascade:FGFR3 (Rattus norvegicus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by FGFR4 (Rattus norvegicus)
Downstream signaling of activated FGFR4 (Rattus norvegicus)
FRS-mediated FGFR4 signaling (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
SHC-mediated cascade:FGFR4 (Rattus norvegicus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by MET (Rattus norvegicus)
MET activates RAS signaling (Rattus norvegicus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
Signalling to ERKs (Rattus norvegicus)
Signalling to RAS (Rattus norvegicus)
p38MAPK events (Rattus norvegicus)
Ral-GDS binds to Ras-GTP (Rattus norvegicus)
Ras-GTP:RalGDS complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by SCF-KIT (Rattus norvegicus)
Activation of RAS by p-KIT bound SOS1 (Rattus norvegicus)
p21 RAS:GDP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated cell proliferation (Rattus norvegicus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Rattus norvegicus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
S-Farn-Me-PalmS KRAS4A [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P08644 Kras
Gene Names
Kras, Kras2
Chain
chain:1-186, initiator methionine:, chain:2-186, propeptide:187-189
Reference Genes
BioGPS Gene:24525 Kras
ENSEMBL:ENSRNOG00055009514 Kras
ENSEMBL:ENSRNOG00060008032 Kras
ENSEMBL:ENSRNOG00065005903 Kras
KEGG Gene (Rattus norvegicus):24525 Kras
Monarch:24525 Kras
NCBI Gene:24525 Kras
UCSC:P08644 Kras
Reference Transcript
RefSeq:NM_031515.3 Kras
RefSeq:XM_017592443.1 Kras
RefSeq:XM_008763354.2 Kras
RefSeq:XM_017592442.1 Kras
Participates
as an output of
p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Rattus norvegicus)
as a member of
S-Farn-Me-PalmS KRAS4A, HRAS, NRAS [plasma membrane] (Rattus norvegicus)
mature p21 RAS [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
phospho-p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane]
KRAS [plasma membrane]
S-Farn-Me KRAS4A [plasma membrane]
S-Farn-Me KRAS4B [cytosol]
phospho-pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane]
phospho-pS181-S-Farn-Me KRAS4B [plasma membrane]
S-Farn-Me PalmS KRAS4A [Golgi membrane]
S-Farn-Me KRAS [endoplasmic reticulum membrane]
S-Farn-Me KRAS4B [endoplasmic reticulum membrane]
S-Farn-KRAS [endoplasmic reticulum membrane]
S-Farn KRAS4B [endoplasmic reticulum membrane]
S-Farn proKRAS4B [endoplasmic reticulum membrane]
S-Farn-proKRAS [endoplasmic reticulum membrane]
proKRAS [cytosol]
pro-KRAS4A [cytosol]
Kras [plasma membrane]
S-Farn-Me KRAS4B [plasma membrane]
Inferred From
S-Farn-Me-PalmS KRAS [plasma membrane]
(Homo sapiens)
S-Farn-Me-PalmS KRAS4A [plasma membrane]
(Homo sapiens)
Modified Residues
Name
S-farnesyl-L-cysteine methyl ester at 186 (in Homo sapiens)
Coordinate
186
PsiMod Name
S-farnesyl-L-cysteine methyl ester
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine methyl ester.
Name
S-palmitoyl-L-cysteine at 180 (in Homo sapiens)
Coordinate
180
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Cross References
RefSeq
XP_017447931.1
,
XP_008761576.1
,
XP_017447932.1
,
NP_113703.1
PRO
P08644
RGD
2981
PDB
1N4S
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