S-Farn-proKRAS [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-9647925
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p21A (K-Ras 2A), Transforming protein p21A, K-Ras 2A, Ki-Ras, c-K-ras
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
KRAS, KRAS2, RASK2
Chain
chain:1-186, initiator methionine:, chain:2-186, propeptide:187-189
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
S-farnesyl-L-cysteine at 186
Coordinate
186
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine.
Interactors (13)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  20 0.695 6
 UniProt:Q99755 PIP5K1A  1 0.661 9
 UniProt:P15056 BRAF  20 0.615 4
 UniProt:Q96II5 Q96II5      0.556 3
 UniProt:P50749 RASF2      0.544 2
 UniProt:P61586 RHOA  6 0.519 2
 UniProt:O75915 ARL6IP5  1 0.519 2
 UniProt:P10398 ARAF  4 0.483 2
 UniProt:P28288 ABCD3  2 0.483 2
 UniProt:P01111 NRAS  20 0.483 2
 UniProt:Q7KZI7 MARK2      0.483 2
 UniProt:Q9UQB8 BAIAP2  1 0.483 2
 ChEBI:16618 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE      0.462 2
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