Reactome | GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-RNO-5689811

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

P19490

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPII-mediated vesicle transport (Rattus norvegicus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Rattus norvegicus)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        CNIH2,3:GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P19490 Gria1

Gene Names

Gria1, Glur1

Chain

signal peptide:1-18, chain:19-907

Reference Genes

BioGPS Gene:50592 Gria1

KEGG Gene (Rattus norvegicus):50592 Gria1

Monarch:50592 Gria1

NCBI Gene:50592 Gria1

UCSC:P19490 Gria1

Reference Transcript

RefSeq:NM_031608.1 Gria1

Participant Of

hasComponent

CNIH2,3:GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Other forms of this molecule

GRIA1 [endoplasmic reticulum membrane]

GRIA1 [ER to Golgi transport vesicle membrane]

GRIA1 [endocytic vesicle membrane]

p-S849-Gria1 [plasma membrane]

Gria1 [plasma membrane]

GRIA1 [plasma membrane]

Inferred From

GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Cross References

RefSeq

NP_113796.1

ZINC target

P19490

PRO

P19490

PDB

6QKZ, 3SAJ, 6NJL, 6NJN, 6QKC, 2AWW, 2G2L

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q71RJ2	2	CACNG2 [endocytic vesicle membrane] (R-RNO-416846) CACNG2 [plasma membrane] (R-RNO-210375)	0.858	7
UniProt:P19491 Gria2	4	phospho-p-S880-GRIA2 [plasma membrane] (R-RNO-3004500) Gria2 [plasma membrane] (R-RNO-9022384) GRIA2 [endocytic vesicle membrane] (R-RNO-3004487) GRIA2 [plasma membrane] (R-RNO-3004502)	0.688	3
UniProt:P19490 Gria1	7	GRIA1 [endoplasmic reticulum membrane] (R-RNO-5689460) GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-RNO-5689811) GRIA1 [ER to Golgi transport vesicle membrane] (R-RNO-5689810) GRIA1 [endocytic vesicle membrane] (R-RNO-3004479) p-S849-Gria1 [plasma membrane] (R-RNO-9620442) Gria1 [plasma membrane] (R-RNO-9620440) GRIA1 [plasma membrane] (R-RNO-3004495)	0.623	2
UniProt:Q5FVC2	1	ARHGEF2 [cytosol] (R-RNO-195101)	0.576	4
UniProt:P11275 Camk2a	6	phospho-p-T286-CAMK2A [nucleoplasm] (R-RNO-444797) phospho-p-T286-CAMK2A [plasma membrane] (R-RNO-432796) phospho-p-T286-CAMK2A [endocytic vesicle membrane] (R-RNO-416999) phospho-p-T286,T305,T306-CAMK2A [cytosol] (R-RNO-4332334) p-T286-Camk2a [cytosol] (R-RNO-9618632) Camk2a [cytosol] (R-RNO-9611390)	0.567	4
UniProt:Q5BJU5	3	CNIH2 [endoplasmic reticulum membrane] (R-RNO-5689442) CNIH2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-RNO-5689781) CNIH2 [ER to Golgi transport vesicle membrane] (R-RNO-5689780)	0.499	3
UniProt:P10608	5	ADRB2 [endosome membrane] (R-RNO-6783036) phospho-pS-ADRB2 [clathrin-coated endocytic vesicle membrane] (R-RNO-8869143) PolyUb-ADRB2 [endosome membrane] (R-RNO-6783066) phospho-pS-ADRB2 [plasma membrane] (R-RNO-8852158) ADRB2 [plasma membrane] (R-RNO-390647)	0.499	3
UniProt:B2GV74	1	KLC2 [cytosol] (R-RNO-983191)	0.499	2
UniProt:P70569	1	MYO5B [cytoplasmic vesicle membrane] (R-RNO-2028712)	0.499	2
UniProt:P31016 Dlg4	3	Dlg4 [cytosol] (R-RNO-6794248) DLG4 [endocytic vesicle membrane] (R-RNO-416847) Dlg4 [plasma membrane] (R-RNO-9612601)	0.462	3