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Ptpn11 [cytosol]
Stable Identifier
R-RNO-548923
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
Shp2, Tyrosine-protein phosphatase non-receptor type 11, PTN11_RAT, Shp-2
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
RET signaling (Rattus norvegicus)
p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
PECAM1 interactions (Rattus norvegicus)
Interaction of PECAM-1 and SHP-2 (Rattus norvegicus)
PECAM-1:SHP-2 complex [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Tie2 Signaling (Rattus norvegicus)
Interaction of Tie2 and Shp2 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
pTie2 and SHP2 complex [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
GPVI-mediated activation cascade (Rattus norvegicus)
G6B binds PTPN6,PTPN11 (Rattus norvegicus)
G6B:PTPN6,PTPN11 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SYK autophosphorylates (Rattus norvegicus)
G6B:PTPN6,PTPN11 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
p-Y7-CLEC1B dimer:PDPN binds SYK (Rattus norvegicus)
G6B:PTPN6,PTPN11 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Platelet homeostasis (Rattus norvegicus)
Platelet sensitization by LDL (Rattus norvegicus)
Interaction of PECAM-1 and SHP-2 (Rattus norvegicus)
PECAM-1:SHP-2 complex [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Costimulation by the CD28 family (Rattus norvegicus)
CTLA4 inhibitory signaling (Rattus norvegicus)
SHP2 phosphatase binds CTLA-4 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PD-1 signaling (Rattus norvegicus)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN6,PTPN11:p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Interaction of SHP-1 or SHP-2 with phospho PD-1 (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN6,PTPN11:p-Y223,248-PDCD1:B7-DC,B7-H1 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SHP-1 and SHP-2 bind pBTLA (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SHP-1/SHP-2:pBTLA:HVEM [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Interferon Signaling (Rattus norvegicus)
Interferon alpha/beta signaling (Rattus norvegicus)
Regulation of IFNA/IFNB signaling (Rattus norvegicus)
Dephosphorylation of STAT1 by SHP2 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-20 family signaling (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:p-Y705-STAT3 [plasma membrane] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:p-Y705-STAT3 [plasma membrane] (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
SHP1 and SHP2 bind the common beta chain (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Interleukin-6 family signaling (Rattus norvegicus)
Interleukin-6 signaling (Rattus norvegicus)
PTPN11 binds CBL (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11:CBL [plasma membrane] (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN11 binds p-Y759-IL6ST (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
PTPN11 is phosphorylated (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF(TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
Activation of IRF3, IRF7 mediated by TBK1, IKBKE (Rattus norvegicus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
GAB1 signalosome (Rattus norvegicus)
Activation of SHP2 through the binding to phospho-Gab1 (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Dephosphorylation of Gab1 by SHP2 (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Dephosphorylation of PAG by SHP2 (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SHP2 dephosphorylates Tyr 992 on EGFR (Rattus norvegicus)
EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Sustained activation of SRC kinase by SHP2 (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Downstream signaling of activated FGFR1 (Rattus norvegicus)
FRS-mediated FGFR1 signaling (Rattus norvegicus)
Activated FGFR1:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR1:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR1:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Negative regulation of FGFR1 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPTN11 dephosphorylates SPRY2 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by FGFR2 (Rattus norvegicus)
Downstream signaling of activated FGFR2 (Rattus norvegicus)
FRS-mediated FGFR2 signaling (Rattus norvegicus)
Activated FGFR2 phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR2:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR2:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Negative regulation of FGFR2 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPTN11 dephosphorylates SPRY2 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by FGFR3 (Rattus norvegicus)
Downstream signaling of activated FGFR3 (Rattus norvegicus)
FRS-mediated FGFR3 signaling (Rattus norvegicus)
Activated FGFR3 phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR3:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR3:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Negative regulation of FGFR3 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPTN11 dephosphorylates SPRY2 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by FGFR4 (Rattus norvegicus)
Downstream signaling of activated FGFR4 (Rattus norvegicus)
FRS-mediated FGFR4 signaling (Rattus norvegicus)
Activated FGFR4 phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Negative regulation of FGFR4 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPTN11 dephosphorylates SPRY2 (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by MET (Rattus norvegicus)
MET activates PTPN11 (Rattus norvegicus)
GAB1 binds PTPN11 (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PTPN11 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
SHP2 binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
Signaling by SCF-KIT (Rattus norvegicus)
Phosphorylation of SHP2 by SFKs (Rattus norvegicus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SHP2 interacts with p-KIT (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Rattus norvegicus)
Ptpn11 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P41499 Ptpn11
Gene Names
Ptpn11
Chain
initiator methionine:1, chain:2-593
Reference Genes
BioGPS Gene:25622 Ptpn11
KEGG Gene (Rattus norvegicus):25622 Ptpn11
Monarch:25622 Ptpn11
NCBI Gene:25622 Ptpn11
UCSC:P41499 Ptpn11
Reference Transcript
RefSeq:NM_013088.2 Ptpn11
RefSeq:NM_001177593.1 Ptpn11
Participates
as an input of
IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Rattus norvegicus)
p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Rattus norvegicus)
Recruitment of Shp-2 to pSirp alpha (Rattus norvegicus)
Interaction of PECAM-1 and SHP-2 (Rattus norvegicus)
Interaction of Tie2 and Shp2 (Rattus norvegicus)
GAB1 binds PTPN11 (Rattus norvegicus)
SHP2 interacts with p-KIT (Rattus norvegicus)
Ntrk2-phosphorylated Frs2 binds Ptpn11 (Homo sapiens)
SHP2 binds to the active receptor (Rattus norvegicus)
PTPN11 binds p-Y759-IL6ST (Rattus norvegicus)
Prlr binds Shp2 (Rattus norvegicus)
SHP2 phosphatase binds CTLA-4 (Rattus norvegicus)
Activated FGFR1:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR2:p-FRS bind to PPTN11 (Rattus norvegicus)
Activation of SHP2 through the binding to phospho-Gab1 (Rattus norvegicus)
Activated FGFR4:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR3:p-FRS bind to PPTN11 (Rattus norvegicus)
as a component of
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Rattus norvegicus)
pSirp alpha:Shp-2 [plasma membrane] (Rattus norvegicus)
PECAM-1:SHP-2 complex [plasma membrane] (Rattus norvegicus)
pTie2 and SHP2 complex [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PTPN11 [plasma membrane] (Rattus norvegicus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Rattus norvegicus)
BDNF:p-5Y-Ntrk2 homodimer:p-Y-Frs2:Ptpn11 [plasma membrane] (Homo sapiens)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Rattus norvegicus)
Prlr ligands:p(Y599)-Prlr:p(Y1007)-Jak2 dimer:Shp2 [plasma membrane] (Rattus norvegicus)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
as a member of
PTPN6,PTPN11 [cytosol] (Rattus norvegicus)
This entity regulates
Negatively
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4
(Rattus norvegicus)
Other forms of this molecule
p-Y-Shp2 [cytosol]
PTPN11 [nucleoplasm]
phospho-p-Y542,Y580-PTPN11 [cytosol]
Inferred From
PTPN11 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_037220.2
,
NP_001171064.1
PRO
P41499
RGD
3447
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P09619 PDGFRB
3
p-11Y-PDGFRB [plasma membrane]
(R-HSA-8864039)
PDGFRB [plasma membrane]
(R-HSA-186767)
p-12Y-PDGFRB [plasma membrane]
(R-HSA-186803)
0.59
4
UniProt:P97710 Sirpa
9
pSirpa_Rat [plasma membrane]
(R-RNO-548918)
Sirpa_Rat [plasma membrane]
(R-RNO-548921)
phospho-Sirpa [plasma membrane]
(R-RNO-391102)
Sirpa [plasma membrane]
(R-RNO-197571-5)
Sirpa [ficolin-1-rich granule membrane]
(R-RNO-6803321)
Sirpa [plasma membrane]
(R-RNO-3209922)
Sirpa [tertiary granule membrane]
(R-RNO-6803288)
Sirpa [plasma membrane]
(R-RNO-197568-5)
Sirpa [secretory granule membrane]
(R-RNO-6804801-5)
0.544
3
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