Ntrk2-phosphorylated Frs2 binds Ptpn11

Stable Identifier
R-NUL-9032361
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Ntrk2-phosphorylated Frs2 binds Ptpn11

Upon phosphorylation of rat Frs2 by rat Ntrk2 (TrkB) activated by human BDNF, phosphorylated Frs2 recruits rat Ptpn11 (Shp2) (Easton et al. 2006).

Literature References
PubMed ID Title Journal Year
16573649 The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor

Easton, JB, Royer, AR, Middlemas, DS

J. Neurochem. 2006
Participants
Orthologous Events
Authored
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