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Mlkl [cytosol]
Stable Identifier
R-RNO-5218901
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
MLKL, A0A8I5ZV82
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
RIPK1:RIPK3 oligomer binds MLKL (Rattus norvegicus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
RIPK3 phosphorylates MLKL (Rattus norvegicus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
Regulation of necroptotic cell death (Rattus norvegicus)
ATP binds MLKL (Rattus norvegicus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4x(MLKL:ATP) [cytosol] (Rattus norvegicus)
MLKL:ATP [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
MLKL binds HSP90:CDC37 (Rattus norvegicus)
MLKL:HSP90:CDC37 [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
Mlkl [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I5ZV82
Gene Names
Mlkl
Reference Genes
BioGPS Gene:690743 Mlkl
ENSEMBL:ENSRNOG00000042353
Monarch:690743 Mlkl
NCBI Gene:690743 Mlkl
UCSC:A0A8I5ZV82 Mlkl
Reference Transcript
RefSeq:XM_008774238.1 Mlkl
RefSeq:XM_008772571.2 Mlkl
RefSeq:XM_003753111.3 Mlkl
RefSeq:XM_008772572.2 Mlkl
RefSeq:XM_008772570.2 Mlkl
RefSeq:XM_006222737.2 Mlkl
RefSeq:XM_006222738.2 Mlkl
RefSeq:XM_008774237.1 Mlkl
Other Identifiers
17733638
5761770
5782018
5893919
6185061
6360339
6428113
6484152
6575101
6659401
6676306
690743
A_44_P520603
A_64_P139138
GO:0003824
GO:0004672
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0007166
GO:0012501
GO:0016740
GO:0019901
GO:0023052
GO:0030054
GO:0036211
GO:0043226
GO:0044877
GO:0051607
GO:0065003
GO:0070207
GO:0070266
GO:0097527
GO:0097528
GO:0098542
GO:0140096
PH_rn_0020326
Participates
as an input of
MLKL binds HSP90:CDC37 (Rattus norvegicus)
RIPK1:RIPK3 oligomer binds MLKL (Rattus norvegicus)
as a component of
MLKL:HSP90:CDC37 [cytosol] (Rattus norvegicus)
MLKL:ATP [cytosol] (Rattus norvegicus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Mlkl [cytosol]
phospho-Mlkl [cytosol]
Inferred From
MLKL [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSRNOG00000042353
,
ENSRNOT00000095360
,
ENSRNOP00000081539
RGD
1592221
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