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Casp8 [cytosol]
Stable Identifier
R-RNO-3465404
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
CASP8(1-374), Q9JHX4
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Caspase activation via extrinsic apoptotic signalling pathway (Rattus norvegicus)
Caspase activation via Death Receptors in the presence of ligand (Rattus norvegicus)
Regulation by c-FLIP (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at DISC (Rattus norvegicus)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
Casp8 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
Regulation of TNFR1 signaling (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at TNFR signaling complex (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
Casp8 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8:FLIP(L) (Rattus norvegicus)
Casp8 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L) [cytosol] (Rattus norvegicus)
Casp8 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
Casp8 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q9JHX4
Gene Names
Casp8
Reference Genes
BioGPS Gene:64044 Casp8
ENSEMBL:ENSRNOG00000012331
ENSEMBL:ENSRNOG00055023227
ENSEMBL:ENSRNOG00060017095
ENSEMBL:ENSRNOG00065029007
KEGG:rno:64044 Casp8
Monarch:64044 Casp8
NCBI Gene:64044 Casp8
UCSC:Q9JHX4 Casp8
Reference Transcript
RefSeq:XM_006245015.5 Casp8
RefSeq:XM_039084164.2 Casp8
RefSeq:NM_022277.2 Casp8
Other Identifiers
10923595
1369262_at
1380297_at
17859543
5755091
5762731
5836514
5842903
5890636
5939525
6222573
6374698
64044
6410446
6502559
6536256
6550784
A_44_P298210
GE1112482
GE1182044
GO:0004197
GO:0005515
GO:0005737
GO:0005829
GO:0006508
GO:0006915
GO:0006954
GO:0008233
GO:0008234
GO:0008625
GO:0030027
GO:0030335
GO:0031264
GO:0031265
GO:0031625
GO:0032731
GO:0032991
GO:0034612
GO:0035877
GO:0036462
GO:0042802
GO:0042981
GO:0043123
GO:0043124
GO:0045651
GO:0045862
GO:0051603
GO:0051604
GO:0060546
GO:0070269
GO:0071260
GO:0097110
GO:0097190
GO:0097191
GO:0097194
GO:0097342
GO:0140639
GO:1900119
ILMN_1371431
PH_rn_0008354
Participates
as a component of
TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
Casp8 [mitochondrial outer membrane]
Casp8 [mitochondrial outer membrane]
Casp8 [cytosol]
Casp8 [cytosol]
Casp8 [cytosol]
Inferred From
CASP8(1-374) [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_071613.1
,
XP_006245077.1
,
XP_038940092.1
ENSEMBL
ENSRNOT00000016613
,
ENSRNOG00000012331
,
ENSRNOP00000016613
PRO
Q9JHX4
RGD
620945
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8R2E7
1
Fadd [cytosol]
(R-RNO-54639)
0.499
2
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