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AKR1C1 [cytosol]
Stable Identifier
R-RNO-2855253-8
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
Q5I0M4
Locations in the PathwayBrowser
Expand all
Drug ADME (Rattus norvegicus)
Prednisone ADME (Rattus norvegicus)
AKR1C1 hydrogenates PREDN,PREDL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonate metabolism (Rattus norvegicus)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
PGH2 is reduced to PGF2a by AKR1C3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of fat-soluble vitamins (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
RA biosynthesis pathway (Rattus norvegicus)
AKR1C3 reduces atRAL to atROL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q5I0M4
Reference Genes
BioGPS Gene:364773
ENSEMBL:ENSRNOG00000033010
KEGG:rno:364773
Monarch:364773
NCBI Gene:364773
UCSC:Q5I0M4
Reference Transcript
RefSeq:NM_001014240.3
Other Identifiers
10799337
17720508
364773
5645077
5649136
5692828
5695132
5797684
5931246
5945349
5969052
6005781
6167094
6300047
6300919
6301210
6337344
6396893
6658321
6679490
6705076
6705583
6716276
A_44_P109562
A_64_P012373
GO:0016491
ILMN_1373236
PH_rn_0018687
Participates
as a member of
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Inferred From
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001014262.3
ENSEMBL
ENSRNOT00000117319
,
ENSRNOG00000033010
,
ENSRNOP00000097567
RGD
1359406
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