Reactome | Fnta [cytosol]

Fnta [cytosol]

Stable Identifier

R-RNO-2530516

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

FNTA(2-379), Q04631

Locations in the PathwayBrowser for interactor UniProt:Q63604 Ntrk2

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External Reference Information

External Reference

UniProt:Q04631

Gene Names

Fnta

Reference Genes

BioGPS Gene:25318 Fnta

ENSEMBL:ENSRNOG00000014462

KEGG:rno:25318 Fnta

Monarch:25318 Fnta

NCBI Gene:25318 Fnta

UCSC:Q04631 Fnta

Reference Transcript

RefSeq:NM_012847.2 Fnta

Participates

as a component of

as an input of

Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha (Rattus norvegicus)

Other forms of this molecule

Fnta [cytosol]

Inferred From

FNTA(2-379) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_036979.2

PRO

Q04631

RGD

2625

PDB

1X81, 1FT2, 3E32, 1D8E, 4GTQ, 2ZIR, 1JCS, 2BED, 1TN7, 1O5M, 1N94, 3KSQ, 1N95, 3E30, 8RDX, 1O1R, 3E33, 2R2L, 7RNI, 2ZIS, 4GTR, 1N4P, 1N4R, 7RN5, 1NL4, 1TNZ, 1N9A, 1TNU, 1FT1, 1NI1, 1O1S, 1SA5, 3DPY, 1JCR, 1TNO, 1O1T, 3EU5, 1TN8, 1FPP, 1S64, 4GTP, 1QBQ, 1TNB, 4GTO, 3E34, 3EUV, 4GTM, 8E9E, 3KSL, 1D8D, 1KZP, 1KZO, 1N4S, 1N4Q, 1TNY, 3PZ4

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q02293	1	FNTB [cytosol] (R-RNO-2530482)	0.951	16
UniProt:P53610	1	PGGT1B [cytosol] (R-RNO-201586)	0.786	7
UniProt:P01116-2 KRAS	8	S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9647815) S-Farn-Me KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649690) S-Farn KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649698) S-Farn proKRAS4B [endoplasmic reticulum membrane] (R-HSA-9649693) pro-KRAS4B [cytosol] (R-HSA-9649686) pS181-S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9653482) S-Farn-Me KRAS4B [cytosol] (R-HSA-9654510) pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane] (R-HSA-9653578)	0.609	3
UniProt:Q63604 Ntrk2	7	phospho-p-5Y-NTRK2 [plasma membrane] (R-RNO-9026475) Ntrk2 [plasma membrane] (R-RNO-179527) p-5Y-Ntrk2 [plasma membrane] (R-RNO-181803) Ntrk2 [Golgi membrane] (R-RNO-189636) Phosphorylated TrkB receptor [Golgi membrane] (R-RNO-189645) p-5Y,S478-Ntrk2 [plasma membrane] (R-RNO-9032964) p-Y705,Y706-Ntrk2 [plasma membrane] (R-RNO-9037061)	0.591	4
UniProt:P62070 RRAS2	1	RRAS2 [plasma membrane] (R-HSA-9715189)	0.589	5

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