Active Plcg1 hydrolyses PIP2

Stable Identifier
R-RNO-182061
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Active Plcg1 hydrolyses PIP2
Inositol 1,4,5-triphosphate (IP3) is a second messenger produced by phospholipase C (PLC) metabolism of phosphoinositol 4,5-bisphosphate (PIP2) (Canossa et al. 2001).
Literature References
PubMed ID Title Journal Year
11285228 Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

Canossa, M, Inagaki, N, Campana, G, Thoenen, H, Gartner, A

EMBO J 2001
Participants
Catalyst Activity

phosphatidylinositol phospholipase C activity of p-Plcg1 [plasma membrane]

Orthologous Events
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