Active PLCG1 hydrolyses PIP2

Stable Identifier
R-HSA-167686
Type
Reaction
Species
Homo sapiens
Compartment
cytoplasmic side of plasma membrane, plasma membrane, cytosol
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Active PLCG1 hydrolyses PIP2
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Inositol 1,4,5-triphosphate (IP3) is a second messenger produced by phospholipase C (PLC) metabolism of phosphoinositol 4,5-bisphosphate (PIP2) (Canossa et al. 2001).

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Input
Output
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as an event of
Catalyst Activity

phosphatidylinositol phospholipase C activity of p-4Y-PLCG1 [plasma membrane]

Physical Entity
p-4Y-PLCG1 [plasma membrane] (Homo sapiens)
Activity
phosphatidylinositol phospholipase C activity (GO:0004435)
Inferred From
Active Plcg1 hydrolyses PIP2 (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2005-11-01)
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