Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TINF2 [nucleoplasm]
Stable Identifier
R-RNO-174883
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
Q5XIB8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Chromosome Maintenance (Rattus norvegicus)
Telomere Maintenance (Rattus norvegicus)
Extension of Telomeres (Rattus norvegicus)
Telomere C-strand (Lagging Strand) Synthesis (Rattus norvegicus)
Disassociation of Processive Complex and Completed Telomere End (Rattus norvegicus)
Extended And Processed Telomere End [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Polymerase switching on the C-strand of the telomere (Rattus norvegicus)
Formation of Processive Complex on the C-strand of the telomere (Rattus norvegicus)
Processive complex loaded on telomere [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive synthesis on the C-strand of the telomere (Rattus norvegicus)
Formation of C-strand Okazaki fragments (Rattus norvegicus)
Processive complex loaded on telomere [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Formation of the Flap Intermediate on the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Joining of adjacent Okazaki fragments of the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Removal of the Flap Intermediate from the C-strand (Rattus norvegicus)
RPA binds to the Flap on the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Recruitment of DNA2 endonuclease to the C strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Removal of remaining Flap from the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomere C-strand synthesis initiation (Rattus norvegicus)
DNA polymerase:primase binds G-strand of the telomere (Rattus norvegicus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Rattus norvegicus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Rattus norvegicus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomere Extension By Telomerase (Rattus norvegicus)
Alignment Of The RNA Template On The Telomeric Chromosome End (Rattus norvegicus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
CDK2:CCNA phosphorylates TERF2 (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Rattus norvegicus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Disassociation of Telomerase RNP and the Chromosome End (Rattus norvegicus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Elongation Of The Telomeric Chromosome End (Rattus norvegicus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Elongation of Extended Telomeric Chromosome End (Rattus norvegicus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
PP6-PPP6R3 dephosphorylates TERF2 (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Rattus norvegicus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Rattus norvegicus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular Senescence (Rattus norvegicus)
DNA Damage/Telomere Stress Induced Senescence (Rattus norvegicus)
Telomere shortening during replicative exhaustion (Rattus norvegicus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
DNA Repair (Rattus norvegicus)
Base Excision Repair (Rattus norvegicus)
Base-Excision Repair, AP Site Formation (Rattus norvegicus)
Depurination (Rattus norvegicus)
Cleavage of the damaged purine (Rattus norvegicus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Rattus norvegicus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
Recognition and association of DNA glycosylase with site containing an affected purine (Rattus norvegicus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
TINF2 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q5XIB8
Reference Genes
BioGPS Gene:290232
ENSEMBL:ENSRNOG00000020189
ENSEMBL:ENSRNOG00000020189.7
KEGG Gene (Rattus norvegicus):290232
Monarch:290232
NCBI Gene:290232
UCSC:Q5XIB8
Reference Transcript
RefSeq:NM_001006962.1
Other Identifiers
10783868
1378387_at
17702996
290232
5632916
5679201
5689883
5729494
5773165
5885655
5932581
5987463
6108925
6156103
6642800
6707039
6728648
A_44_P260268
GE1184039
GO:0005634
GO:0005694
GO:0016233
GO:0032200
GO:0043226
GO:0070187
PH_rn_0006127
rc_AA965244_at
Participates
as a component of
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Inferred From
TINF2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001006963.1
Ensembl
ENSRNOP00000027362
,
ENSRNOG00000020189
,
ENSRNOT00000027362
RGD
1359192
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
