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Shelterin complex [nucleoplasm]
Stable Identifier
R-RNO-174898
Type
Complex
Species
Rattus norvegicus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Chromosome Maintenance (Rattus norvegicus)
Telomere Maintenance (Rattus norvegicus)
Extension of Telomeres (Rattus norvegicus)
Telomere C-strand (Lagging Strand) Synthesis (Rattus norvegicus)
Disassociation of Processive Complex and Completed Telomere End (Rattus norvegicus)
Extended And Processed Telomere End [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Polymerase switching on the C-strand of the telomere (Rattus norvegicus)
Formation of Processive Complex on the C-strand of the telomere (Rattus norvegicus)
Processive complex loaded on telomere [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive synthesis on the C-strand of the telomere (Rattus norvegicus)
Formation of C-strand Okazaki fragments (Rattus norvegicus)
Processive complex loaded on telomere [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Formation of the Flap Intermediate on the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Joining of adjacent Okazaki fragments of the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Removal of the Flap Intermediate from the C-strand (Rattus norvegicus)
RPA binds to the Flap on the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Recruitment of DNA2 endonuclease to the C strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Removal of remaining Flap from the C-strand (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomere C-strand synthesis initiation (Rattus norvegicus)
DNA polymerase:primase binds G-strand of the telomere (Rattus norvegicus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Rattus norvegicus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Rattus norvegicus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomere Extension By Telomerase (Rattus norvegicus)
Alignment Of The RNA Template On The Telomeric Chromosome End (Rattus norvegicus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
CDK2:CCNA phosphorylates TERF2 (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Disassociation of Telomerase RNP and the Chromosome End (Rattus norvegicus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Elongation Of The Telomeric Chromosome End (Rattus norvegicus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Elongation of Extended Telomeric Chromosome End (Rattus norvegicus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
PP6-PPP6R3 dephosphorylates TERF2 (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Rattus norvegicus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular Senescence (Rattus norvegicus)
DNA Damage/Telomere Stress Induced Senescence (Rattus norvegicus)
Telomere shortening during replicative exhaustion (Rattus norvegicus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
DNA Repair (Rattus norvegicus)
Base Excision Repair (Rattus norvegicus)
Base-Excision Repair, AP Site Formation (Rattus norvegicus)
Depurination (Rattus norvegicus)
Cleavage of the damaged purine (Rattus norvegicus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Rattus norvegicus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
Recognition and association of DNA glycosylase with site containing an affected purine (Rattus norvegicus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Shelterin complex [nucleoplasm] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Acd [nucleoplasm]
(Rattus norvegicus)
Pot1 [nucleoplasm]
(Rattus norvegicus)
TERF1 homodimer [nucleoplasm]
(Rattus norvegicus)
TERF2 homodimer [nucleoplasm]
(Rattus norvegicus)
x 2
Terf2ip [nucleoplasm]
(Rattus norvegicus)
TINF2 [nucleoplasm]
(Rattus norvegicus)
Participates
as a component of
AP-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Rattus norvegicus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Rattus norvegicus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Rattus norvegicus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Rattus norvegicus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Rattus norvegicus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Rattus norvegicus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Rattus norvegicus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Rattus norvegicus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Rattus norvegicus)
Extended And Processed Telomere End [nucleoplasm] (Rattus norvegicus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Rattus norvegicus)
as an output of
Telomere shortening during replicative exhaustion (Rattus norvegicus)
Inferred From
Shelterin complex [nucleoplasm]
(Homo sapiens)
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