Reactome | PKLR-2 [cytosol]

PKLR-2 [cytosol]

Stable Identifier

R-PFA-211388

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

cytosol

Synonyms

C6KTA4

Locations in the PathwayBrowser

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Metabolism (Plasmodium falciparum)

- Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
  - Pyruvate metabolism (Plasmodium falciparum)
    - PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
      - pyruvate kinase tetramer [cytosol] (Plasmodium falciparum)
        
        pyruvate kinase complex, liver and RBC [cytosol] (Plasmodium falciparum)
        
        PKLR-2 [cytosol] (Plasmodium falciparum)
- Metabolism of carbohydrates and carbohydrate derivatives (Plasmodium falciparum)
  - Glucose metabolism (Plasmodium falciparum)
    - Glycolysis (Plasmodium falciparum)
      - PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
        
        pyruvate kinase tetramer [cytosol] (Plasmodium falciparum)
        
        pyruvate kinase complex, liver and RBC [cytosol] (Plasmodium falciparum)
        
        PKLR-2 [cytosol] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:C6KTA4

Reference Genes

BioGPS Gene:3885761

ENSEMBL:PF3D7_0626800

KEGG:pfa:PF3D7_0626800

Monarch:3885761

NCBI Gene:3885761

PlasmoDB:PF3D7_0626800

UCSC:C6KTA4

Reference Transcript

RefSeq:XM_961158.1

Participates

as a component of

pyruvate kinase complex, liver and RBC [cytosol] (Plasmodium falciparum)

Other forms of this molecule

PKM [secretory granule lumen]

PKM [extracellular region]

PKM [ficolin-1-rich granule lumen]

PolyUb-PKM-1 [cytosol]

PKM-2 [cytosol]

PKM [nucleoplasm]

Inferred From

Pyruvate kinase, R/L type [cytosol] (Homo sapiens)

PKLR-2 [cytosol] (Homo sapiens)

PKLR-1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_966251.1

PDB

7Z4M, 7Z4N, 7Z4Q, 7Z4R, 3KHD, 6KSH

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