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PKLR-2 [cytosol]
Stable Identifier
R-HSA-211388
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
PKLR isozyme L, PKLR isoform 2, Pyruvate kinase, L isozyme, pyruvate kinase, liver and RBC, Red cell/liver pyruvate kinase
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in beta cells (Homo sapiens)
HNF1A-dependent synthesis of the L isoform of PKLR protein (Homo sapiens)
PKLR-2 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
phosphoenolpyruvate + ADP => pyruvate + ATP (Homo sapiens)
pyruvate kinase tetramer [cytosol] (Homo sapiens)
pyruvate kinase complex, liver and RBC [cytosol] (Homo sapiens)
Pyruvate kinase, R/L type [cytosol] (Homo sapiens)
PKLR-2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P30613-2 PKLR
Gene Names
PKLR, PK1, PKL
Other Identifiers
0000510113
0005550215
0006620278
11730104_a_at
11730105_a_at
11740858_a_at
16694158
207858_s_at
210451_at
222078_at
2437364
2437365
2437366
2437367
2437368
2437369
2437370
2437371
2437372
2437373
2437374
2437375
2437376
2437377
2437378
2437379
2437380
37077_at
5313
7920744
92008_s_at
A_23_P201022
A_24_P325533
D10326_s_at
GE60479
GO:0000166
GO:0000287
GO:0001666
GO:0003674
GO:0003824
GO:0004743
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005829
GO:0005975
GO:0006091
GO:0006096
GO:0006754
GO:0006950
GO:0007584
GO:0008150
GO:0008152
GO:0009056
GO:0009058
GO:0009408
GO:0009749
GO:0010038
GO:0010226
GO:0016301
GO:0016310
GO:0016740
GO:0030955
GO:0032869
GO:0033198
GO:0034641
GO:0042866
GO:0043167
GO:0043226
GO:0044281
GO:0046872
GO:0051591
GO:0061621
GO:0070062
GO:0071872
Hs.284171.0.A1_3p_at
ILMN_1723644
ILMN_1725172
ILMN_1777031
ILMN_2279397
ILMN_2380561
M15465_s_at
PH_hs_0005223
TC01003312.hg
g10835120_3p_a_at
g189995_3p_at
Participant Of
output
HNF1A-dependent synthesis of the L isoform of PKLR protein
hasMember
Pyruvate kinase, R/L type [cytosol]
Inferred To
pyk1 [cytosol] (Schizosaccharomyces pombe)
PKLR-2 [cytosol] (Plasmodium falciparum)
Pklr [cytosol] (Mus musculus)
Pklr [cytosol] (Rattus norvegicus)
PKLR [cytosol] (Bos taurus)
PKLR [cytosol] (Sus scrofa)
pyk [cytosol] (Dictyostelium discoideum)
pyk-2 [cytosol] (Caenorhabditis elegans)
CDC19 [cytosol] (Saccharomyces cerevisiae)
pklr [cytosol] (Danio rerio)
adcy4 [cytosol] (Xenopus tropicalis)
PyK [cytosol] (Drosophila melanogaster)
Cross References
RefSeq
NP_870986.1
,
NP_000289.1
OpenTargets
ENSG00000143627
GeneCards
P30613
HPA
ENSG00000143627-PKLR
ZINC target
P30613
Ensembl
ENSG00000143627
,
ENST00000571194
,
ENSP00000376214
,
ENSP00000339933
,
ENST00000342741
,
ENSP00000459921
,
ENSG00000262785
,
ENST00000392414
,
ENSP00000461487
,
ENST00000572740
PRO
P30613
Orphanet
15101
HMDB Protein
HMDBP00765
PDB
2VGB
,
2VGI
,
4IP7
,
6NN8
,
2VGF
,
6NN5
,
4IMA
,
6NN4
,
6NN7
,
2VGG
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