Reactome | RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160

RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160

Stable Identifier

R-HSA-9615945

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

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RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160

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Based on studies with recombinant human proteins and Xenopus egg extracts, RAN:GTP binds to transportin (TNPO1) or importin beta (KPNB1) associated with the Nup107-160 complex (Lau et al. 2009), resulting in release of the latter.

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Output