GSK3B phosphorylates Runx2

Stable Identifier
R-NUL-9008636
Type
Reaction [transition]
Species
Homo sapiens
Compartment
General
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GSK3B phosphorylates Runx2

Recombinant human GSK3B phosphorylates recombinant mouse Runx2 on three serine residues in an evolutionarily conserved motif SPPWSYDQS (Kugimiya et al. 2007).

Literature References
PubMed ID Title Journal Year
17786208 GSK-3beta controls osteogenesis through regulating Runx2 activity

Kugimiya, F, Kawaguchi, H, Ohba, S, Kawamura, N, Hirata, M, Chikuda, H, Azuma, Y, Woodgett, JR, Nakamura, K, Chung, UI

PLoS ONE 2007
Participants
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of Runx2:GSK3B [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created