TGFBR1 is recruited to tight junction by binding Pard6a

Stable Identifier
R-NUL-2161147
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
TGFBR1 is recruited to tight junction by binding Pard6a

FLAG-tagged mouse Pard6a exogenously expressed in human embryonic kidney cell line, HEK293, binds HA-tagged human TGFBR1. According to studies in confluent normal murine mammary monolayers, NMuMG, exogenous human Myc-tagged TGFBR1 and exogenously expressed mouse FLAG-tagged Pard6a co-localize with endogenous ZO1 protein, a marker of tight junctions (Ozdamar et al. 2005).

Literature References
PubMed ID Title Journal Year
15761148 Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

Barrios-Rodiles, M, Zhang, Y, Wrana, JL, Wang, HR, Bose, R, Ozdamar, B

Science 2005
Participants
Orthologous Events
Authored
Reviewed
Created
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