Reactome | TGFBR1 homodimer [plasma membrane]

TGFBR1 homodimer [plasma membrane]

Stable Identifier

R-HSA-170864

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Type I receptor dimer

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
  - Signaling by TGF-beta Receptor Complex in Cancer (Homo sapiens)
    - Loss of Function of TGFBR2 in Cancer (Homo sapiens)
      - TGFBR2 Kinase Domain Mutants in Cancer (Homo sapiens)
        
        TGFBR2 KD mutants do not phosphorylate TGFBR1 (Homo sapiens)
        
        TGFB1:TGFBR2 KD Mutants:TGFBR1 [plasma membrane] (Homo sapiens)
        
        TGFBR1 homodimer [plasma membrane] (Homo sapiens)

Participants

components

x 2 TGFBR1 [plasma membrane] (Homo sapiens)

Participates

as a component of

as an input of

TGFBR1 is recruited to tight junction by binding Pard6a (Homo sapiens)

Inferred To

TGFBR1 homodimer [plasma membrane] (Bos taurus)

TGFBR1 homodimer [plasma membrane] (Caenorhabditis elegans)

TGFBR1 homodimer [plasma membrane] (Canis familiaris)

TGFBR1 homodimer [plasma membrane] (Danio rerio)

TGFBR1 homodimer [plasma membrane] (Drosophila melanogaster)

TGFBR1 homodimer [plasma membrane] (Gallus gallus)

TGFBR1 homodimer [plasma membrane] (Mus musculus)

TGFBR1 homodimer [plasma membrane] (Rattus norvegicus)

TGFBR1 homodimer [plasma membrane] (Sus scrofa)

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