Human APC is finally phosphorylated by Murine GSK3beta

Stable Identifier
R-NUL-209144
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Human APC is finally phosphorylated by Murine GSK3beta
Human APC is finally phosphorylated by Murine GSK3beta
Literature References
PubMed ID Title Journal Year
15327768 Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

Ha, NC, Tonozuka, T, Stamos, JL, Choi, HJ, Weis, WI

Mol Cell 2004
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of GSK3beta [cytosol]

Physical Entity
GSK3beta [cytosol] (Mus musculus)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
Further phosphorylation of APC by SGG (Drosophila melanogaster)
Authored
Williams, MG  (2006-07-26)
Reviewed
Nusse, R  (2008-01-19)
Created
Williams, MG  (2006-10-24)
Cite Us!