Roel Nusse

 ORCID
Reviewed Pathways (12/12)
Date Identifier Pathway Reference
2008-01-19 R-DME-209412 Wingless pathway BibTex
2008-01-19 R-DME-209441 WG ligand not bound to FZ receptors BibTex
2008-01-19 R-DME-209413 Assembly of the 'destruction complex' BibTex
2008-01-19 R-DME-209155 Phosphorylation of AXN and APC BibTex
2008-01-19 R-DME-209396 Phosphorylation of ARM BibTex
2008-01-19 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM BibTex
2008-01-19 R-DME-209469 WG ligand bound to FZ receptors BibTex
2008-01-19 R-DME-209472 Assembly of receptor complex BibTex
2008-01-19 R-DME-209387 Phosphorylation of ARR BibTex
2008-01-19 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM BibTex
2008-01-19 R-DME-209407 Transport of ARM to the nucleus BibTex
2008-01-19 R-DME-209421 Transcription activation by ARM BibTex
Reviewed Reactions (15/35)
Date Identifier Reaction Reference
2008-01-19 R-MMU-209096 Murine Axin1 is dephosphorylated by PP2A leading to reduced binding affinity with beta-catenin BibTex
2008-01-19 R-DME-209107 Further phosphorylation of APC by DCO BibTex
2008-01-19 R-NUL-209065 Human APC is further phosphorylated by Murine CKIepsilon BibTex
2008-01-19 R-DME-209049 Phosphorylation of AXN and APC by SGG BibTex
2008-01-19 R-NUL-209060 Human APC is further phosphorylated by Murine GSK3beta BibTex
2008-01-19 R-NUL-209146 Murine Axin1 is further phosphorylated by Human GSK3beta BibTex
2008-01-19 R-DME-209143 Phosphorylation of AXN and APC by DCO BibTex
2008-01-19 R-NUL-209132 Human APC is initially phosphorylated by Murine CKIepsilon BibTex
2008-01-19 R-DME-209133 Formation of the 'destruction complex' BibTex
2008-01-19 R-MMU-209059 Murine CKIepsilon binds to Murine Axin1 BibTex
2008-01-19 R-MMU-209148 Murine CKIalpha binds to Murine Axin1 BibTex
2008-01-19 R-DME-209081 Disassembly of the destabilised 'destruction complex' BibTex
2008-01-19 R-DME-209075 Destabilisation and degradation of AXN in the 'destruction complex' BibTex
2008-01-19 R-DME-209112 Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM BibTex
2008-01-19 R-DME-209120 Membrane recruitment of DSH to FZ and AXN to phosphorylated ARR BibTex