mFz8CRD binds LRP6N in vitro

Stable Identifier
R-NUL-1458871
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
mFz8CRD binds LRP6N in vitro
HEK293 cells were transiently transfected with constructs encoding the extracellular regions of mouse Frizzled8 and human LRP6, and co-immunoprecipitations were performed from conditioned medium. The association between mFzd8CRD and LRP6N was dependent on mWnt1.
Literature References
PubMed ID Title Journal Year
11029007 LDL-receptor-related proteins in Wnt signal transduction

Saint-Jeannet, JP, Kato, Y, Tamai, K, Katsuyama, Y, Spokony, R, Hess, F, He, X, Semenov, M, Liu, C

Nature 2000
Participants
Input
Output
Orthologous Events
WNT binds to FZD and LRP5/6 (Homo sapiens)
Authored
Rothfels, K  (2013-05-30)
Reviewed
Rajakulendran, N  (2014-01-22)
van Amerongen, R  (2014-02-15)
Created
Rothfels, K  (2011-07-23)
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