sulfate uptake in the cytosol

Stable Identifier
R-MTU-936631
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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sulfate uptake in the cytosol
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The sulfate transporter of M. tuberculosis, a typical ABC transporter family ATPase, is the sole membrane transport protein in sulfate assimilation. It consists of the CysT/CysW/CysA proteins in 1:1:2 stoichiometry. cysA null mutants in M. bovis were unable to take up sulfate but could be rescued by M. tuberculosis cysA (Wooff et al, 2002).
Literature References
PubMed ID Title Journal Year
11929522 Functional genomics reveals the sole sulphate transporter of the Mycobacterium tuberculosis complex and its relevance to the acquisition of sulphur in vivo

Wooff, E, Michell, SL, Gordon, SV, Chambers, MA, Bardarov, S, Jacobs WR, Jr, Hewinson, RG, Wheeler, PR

Mol Microbiol 2002
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Catalyst Activity

ABC-type sulfate transporter activity of sulfate ABC transporter [plasma membrane]

Physical Entity
sulfate ABC transporter [plasma membrane] (Mycobacterium tuberculosis)
Activity
ABC-type sulfate transporter activity (GO:0015419)
Authored
Stephan, R  (2010-06-17)
Reviewed
Warner, D  (2010-11-25)
Created
Jassal, B  (2010-08-24)
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