Mitf-m binds Smarca4, Smarcb1, Smarce1, Smarcd1

Stable Identifier
R-MMU-9855909
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Mitf-m binds Smarca4, Smarcb1, Smarce1, Smarcd1
Mitf-M interacts with SWI/SNF complex components Smarca4 (Brg1), Smarcb1 (Ini1) and Smarc31 (Baf57) in mouse melanoma B16 cells as assessed by co-immunoprecipitation (de la Serna et al, 2006). Mitf-m and the SWI/SNF contribute to the expression of melanogenic genes such as Tyr, Tyrp1 and Pmel17 (de la Serna et al, 2006; Aras et al, 2019).
Literature References
PubMed ID Title Journal Year
16648630 The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes

de la Serna, IL, Ohkawa, Y, Higashi, C, Dutta, C, Osias, J, Kommajosyula, N, Tachibana, T, Imbalzano, AN

J Biol Chem 2006
30515787 BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation

Aras, S, Saladi, SV, Basuroy, T, Marathe, HG, Lorès, P, de la Serna, IL

J Cell Physiol 2019
Participants
Input
Output
Orthologous Events
MITF-M and the SWI/SNF complex bind the TYR promoter (Homo sapiens)
Authored
Rothfels, K  (2023-12-21)
Reviewed
Arnheiter, H  (2024-02-26)
de la Serna, IL  (2024-05-21)
Vu, HN  (2024-11-05)
Steingrímsson, E  (2024-11-05)
Created
Rothfels, K  (2023-12-07)
Cite Us!