Neil3 cleaves spirominodihydantoin from telomeric DNA oligomer

Stable Identifier
R-MMU-9629485
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Neil3 cleaves spirominodihydantoin from telomeric DNA oligomer

Mouse Neil3 cleaves oxidatively damaged guanine in the form of spiroiminodihydantoin (Sp) from telomeric DNA oligomer (Zhou et al. 2013).

Literature References
PubMed ID Title Journal Year
23926102 Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context

Burrows, CJ, Liu, M, Fleming, AM, Wallace, SS, Zhou, J

J. Biol. Chem. 2013
Participants
Catalyst Activity

DNA N-glycosylase activity of Neil3:Sp-Telomeric DNA oligomer [nucleoplasm]

Orthologous Events
Authored
Reviewed
Created
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