Lyn, p-Syk phosphorylate Btk

Stable Identifier
R-MMU-9607032
Type
Reaction [transition]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Lyn, p-Syk phosphorylate Btk
A Src family kinase (Lyn) phosphorylates Btk on tyrosine-551 (Rawlings et al. 1996).
Literature References
PubMed ID Title Journal Year
8629002 Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

Rawlings, DJ, Scharenberg, AM, Park, H, Wahl, MI, Lin, S, Kato, RM, Fluckiger, AC, Witte, ON, Kinet, JP

Science 1996
Participants
Input
Output
Catalyst Activity

protein tyrosine kinase activity of Lyn, p-Syk [cytosol]

Physical Entity
Lyn, p-Syk [cytosol] (Mus musculus)
Activity
protein tyrosine kinase activity (GO:0004713)
Orthologous Events
p-SYK and LYN phosphorylate BTK (Homo sapiens)
Authored
May, B  (2018-04-26)
Reviewed
Wienands, J  (2018-07-18)
Created
May, B  (2018-04-30)
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