Reactome | Cd3d [clathrin-coated endocytic vesicle membrane]

Cd3d [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-MMU-8869079

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

CD3D, P04235

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - Clathrin-mediated endocytosis (Mus musculus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - RAB5 and GAPVD1 bind AP-2 (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Cd3d [clathrin-coated endocytic vesicle membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P04235

Gene Names

Cd3d

Reference Genes

BioGPS Gene:12500 Cd3d

ENSEMBL:ENSMUSG00000032094

KEGG:mmu:12500 Cd3d

Monarch:12500 Cd3d

NCBI Gene:12500 Cd3d

UCSC:P04235 Cd3d

Reference Transcript

RefSeq:NM_013487.3 Cd3d

Other Identifiers

10584821

12500

1422828_at

17516691

4306846

4404815

4419644

4488102

4492484

4562309

4644653

4727657

4857150

5205364

5292104

92683_at

A_51_P285206

A_66_P109615

GE36570

GO:0002250

GO:0002376

GO:0004888

GO:0005515

GO:0005886

GO:0007166

GO:0009897

GO:0016020

GO:0042101

GO:0042105

GO:0042110

GO:0042802

GO:0045059

GO:0065003

ILMN_2697415

ILMN_2697420

mMC008893

x02339_s_at

Participates

as a member of

AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)

Other forms of this molecule

Cd3d [plasma membrane]

phospho-Cd3d [plasma membrane]

Inferred From

CD3D [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_038515.3

ENSEMBL

ENSMUST00000034602, ENSMUSG00000032094, ENSMUSP00000034602

PRO

P04235

GlyGen

P04235

MGI

88331

Cite Us!