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TNFSF10:TNFRSF10A,B:FADD [plasma membrane]
Stable Identifier
R-MMU-5637464
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Caspase activation via extrinsic apoptotic signalling pathway (Mus musculus)
Caspase activation via Death Receptors in the presence of ligand (Mus musculus)
Dimerization of procaspase-8 (Mus musculus)
TRAIL-mediated dimerization of procaspase-8 (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
Regulation by c-FLIP (Mus musculus)
Caspase-8 and FLIP(L) processing at DISC (Mus musculus)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Mus musculus)
DISC [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Mus musculus)
DISC:procaspase-8 [plasma membrane] (Mus musculus)
DISC [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
CASP8 activity is inhibited (Mus musculus)
FLIP(L) and procaspase-8 form heterodimer (Mus musculus)
DISC:procaspase-8 [plasma membrane] (Mus musculus)
DISC [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Mus musculus)
DISC:procaspase-8 [plasma membrane] (Mus musculus)
DISC [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
FLIP(S) and procaspase-8 form heterodimer (Mus musculus)
DISC:procaspase-8 [plasma membrane] (Mus musculus)
DISC [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Mus musculus)
DISC:procaspase-8 [plasma membrane] (Mus musculus)
DISC [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TRAIL signaling (Mus musculus)
TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
TRAIL:TRAIL receptor trimers bind FADD (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
Fadd [cytosol]
(Mus musculus)
TNFSF10:TNFRSF10A,B Trimer [plasma membrane]
(Mus musculus)
Participates
as a component of
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane] (Mus musculus)
as an input of
TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Mus musculus)
as an output of
TRAIL:TRAIL receptor trimers bind FADD (Mus musculus)
as a member of
DISC [plasma membrane] (Mus musculus)
Inferred From
TNFSF10:TNFRSF10A,B:FADD [plasma membrane]
(Homo sapiens)
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