Reactome | Rasgrf1 [plasma membrane]

Rasgrf1 [plasma membrane]

Stable Identifier

R-MMU-442723

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

RASGRF1, P27671

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- MAPK family signaling cascades (Mus musculus)
  - MAPK1/MAPK3 signaling (Mus musculus)
    - RAF/MAP kinase cascade (Mus musculus)
      - RAS GEFs promote RAS nucleotide exchange (Mus musculus)
        
        RAS GEFs [plasma membrane] (Mus musculus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
        
        RASGRF1 oligomer [plasma membrane] (Mus musculus)
        
        RASGRF1 homooligomer [plasma membrane] (Mus musculus)
        
        Rasgrf1 [plasma membrane] (Mus musculus)
        
        RASGRF1:RASGRF2 heterooligomer [plasma membrane] (Mus musculus)
        
        Rasgrf1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P27671

Gene Names

Rasgrf1

Reference Genes

BioGPS Gene:19417 Rasgrf1

ENSEMBL:ENSMUSG00000032356

KEGG:mmu:19417 Rasgrf1

Monarch:19417 Rasgrf1

NCBI Gene:19417 Rasgrf1

UCSC:P27671 Rasgrf1

Reference Transcript

RefSeq:NM_011245.2 Rasgrf1

Other Identifiers

10587699

137987_at

138123_at

1422600_at

1424734_at

1435614_s_at

1459056_at

17520198

19417

4388330

4392950

4406438

4446146

4467209

4535438

4567414

4581139

4626770

4627581

4636396

4640486

4650383

4656188

4696871

4712268

4732355

4737212

4780666

4837065

4886891

5038873

5055218

5086017

5141500

5155604

5190146

5229671

5247746

5254348

5265884

5286118

5288340

5348302

5401674

5455018

5502333

5511619

5524462

96313_at

A_52_P536022

A_52_P536025

A_52_P550393

A_52_P671676

GE33367

GE35991

GO:0005085

GO:0005515

GO:0005829

GO:0005886

GO:0007264

GO:0007265

GO:0030426

GO:0031175

GO:0034976

GO:0035022

GO:0035254

GO:0035556

GO:0043410

GO:0044342

GO:0046578

GO:0046579

GO:0048167

GO:0048168

ILMN_1219055

ILMN_1233146

ILMN_2560053

ILMN_2699663

ILMN_2774877

ILMN_3055230

ILMN_3132050

Msa.10764.0_s_at

Msa.77.0_f_at

l20899_f_at

mMC001903

Participates

as a component of

Inferred From

RASGRF1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_035375.1

ENSEMBL

ENSMUST00000034912, ENSMUSG00000032356, ENSMUSP00000034912

PRO

P27671

GlyGen

P27671

MGI

99694

PDB

2IJE

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q63604 Ntrk2	7	phospho-p-5Y-NTRK2 [plasma membrane] (R-RNO-9026475) Ntrk2 [plasma membrane] (R-RNO-179527) p-5Y-Ntrk2 [plasma membrane] (R-RNO-181803) Ntrk2 [Golgi membrane] (R-RNO-189636) Phosphorylated TrkB receptor [Golgi membrane] (R-RNO-189645) p-5Y,S478-Ntrk2 [plasma membrane] (R-RNO-9032964) p-Y705,Y706-Ntrk2 [plasma membrane] (R-RNO-9037061)	0.524	2
UniProt:P35739 Ntrk1	7	Phosphorylated TrkA receptor [Golgi membrane] (R-RNO-189653) Ntrk1 [Golgi membrane] (R-RNO-189650) phospho-p-5Y-NTRK1-1 [endosome membrane] (R-RNO-190064) Phosphorylated TrkA receptor [plasma membrane] (R-RNO-181844) TrkA receptor [plasma membrane] (R-RNO-179526) NTRK1 [plasma membrane] (R-RNO-3008784) phospho-p-5Y-NTRK1 [plasma membrane] (R-RNO-3009413)	0.524	3
UniProt:Q03351 Ntrk3	6	Phosphorylated TrkC receptor [Golgi membrane] (R-RNO-189649) Ntrk3 [Golgi membrane] (R-RNO-189625) NTRK3 [plasma membrane] (R-RNO-6798240) p-5Y-Ntrk3 [plasma membrane] (R-RNO-181845) Ntrk3 [plasma membrane] (R-RNO-179528) phospho-p-5Y-NTRK3 [plasma membrane] (R-RNO-9034718)	0.524	2