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phospho-p-5Y-NTRK1 [plasma membrane]
Stable Identifier
R-RNO-3009413
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
P35739
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
Activation of TRKA receptors (Rattus norvegicus)
TRKA activation by NGF (Rattus norvegicus)
Activated TrkA receptor internalizes to endosomes (Rattus norvegicus)
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
PI3K/AKT activation (Rattus norvegicus)
Active IRS recruits PI3K to the plasma membrane and activates it (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
PI3K produces PIP3 and other phosphatidyl inositides (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
Retrograde neurotrophin signalling (Rattus norvegicus)
Axonal transport of NGF:Trk complexes (Rattus norvegicus)
Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
Signalling to ERKs (Rattus norvegicus)
Prolonged ERK activation events (Rattus norvegicus)
ARMS-mediated activation (Rattus norvegicus)
ARMS is phosphorylated by active TrkA receptor (Rattus norvegicus)
Active TrkA receptor:ARMS:Crk complex [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
C3G stimulates nucleotide exchange on Rap1 (Rattus norvegicus)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
Crk's SH3 domain engages C3G (Rattus norvegicus)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P35739 Ntrk1
Gene Names
Ntrk1, Trk, Trka
Chain
signal peptide:1-32, chain:33-799
Reference Genes
BioGPS Gene:59109 Ntrk1
ENSEMBL:ENSRNOG00000013953.9 Ntrk1
ENSEMBL:ENSRNOG00055023126 Ntrk1
ENSEMBL:ENSRNOG00060031729 Ntrk1
ENSEMBL:ENSRNOG00065029663 Ntrk1
KEGG Gene (Rattus norvegicus):59109 Ntrk1
Monarch:59109 Ntrk1
NCBI Gene:59109 Ntrk1
UCSC:P35739 Ntrk1
Reference Transcript
RefSeq:NM_021589.1 Ntrk1
Other Identifiers
10824188
1369000_at
17748555
5645907
5823701
5835472
59109
6015104
6045832
6063660
6155166
6290771
6306265
6353766
6369415
6400183
6479369
6519504
6538508
6539034
6610541
6614150
6620970
6676650
6716900
A_42_P780039
A_64_P115417
GE20747
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005030
GO:0005515
GO:0005524
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005886
GO:0006468
GO:0007169
GO:0007399
GO:0007623
GO:0008285
GO:0009986
GO:0010465
GO:0010976
GO:0012501
GO:0016020
GO:0016740
GO:0023052
GO:0030154
GO:0030183
GO:0030424
GO:0031410
GO:0034330
GO:0036211
GO:0038180
GO:0042490
GO:0042802
GO:0042803
GO:0043226
GO:0043235
GO:0043524
GO:0046579
GO:0048011
GO:0048406
GO:0048485
GO:0048856
GO:0051402
GO:0051965
GO:0060089
GO:0060384
GO:0060385
GO:0061368
GO:0140096
GO:1990090
ILMN_1370831
M85214_at
PH_rn_0011613
Participates
as a component of
Activated TrkA receptor complex [plasma membrane] (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
Phosphorylated TrkA receptor [Golgi membrane]
Ntrk1 [Golgi membrane]
phospho-p-5Y-NTRK1-1 [endosome membrane]
Phosphorylated TrkA receptor [plasma membrane]
TrkA receptor [plasma membrane]
NTRK1 [plasma membrane]
Inferred From
p-5Y-NTRK1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 496 (in Homo sapiens)
Coordinate
496
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 676 (in Homo sapiens)
Coordinate
676
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 680 (in Homo sapiens)
Coordinate
680
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 681 (in Homo sapiens)
Coordinate
681
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 791 (in Homo sapiens)
Coordinate
791
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_067600.1
IntEnz
2.7.10.1
Ensembl
ENSRNOT00000115670
,
ENSRNOP00000018961
,
ENSRNOG00000013953
,
ENSRNOP00000079821
,
ENSRNOT00000018961
PRO
P35739
RGD
620144
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62994 Grb2
3
Grb2 [cytosol]
(R-RNO-55929)
Grb2 [plasma membrane]
(R-RNO-202993)
Grb2 [cytosol]
(R-RNO-74686)
0.548
6
ChEBI:62935 DHEA-7-CMO
0.544
5
UniProt:P27671
1
Rasgrf1 [plasma membrane]
(R-MMU-442723)
0.524
3
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