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Basic fibroblast growth factor receptor 1 [plasma membrane]
Stable Identifier
R-MMU-420339
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
Fgfr1, FGFR1_MOUSE
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
L1CAM interactions (Mus musculus)
Signal transduction by L1 (Mus musculus)
L1-FGFR cis-heterodimerization (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
L1:FGFR1 [plasma membrane] (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by FGFR (Mus musculus)
Signaling by FGFR1 (Mus musculus)
FGFR1 ligand binding and activation (Mus musculus)
FGFR1c and Klotho ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Mus musculus)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Mus musculus)
FGFR-1 homodimer [plasma membrane] (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
FGFR1c binds to Klotho-bound FGF23 (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Mus musculus)
FGFR-1 homodimer [plasma membrane] (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
FGFR1c ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR1c (Mus musculus)
FGFR1c homodimer bound to FGF [plasma membrane] (Mus musculus)
FGFR-1 homodimer [plasma membrane] (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
FGFR1c binds to FGF (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
FGFR1c homodimer bound to FGF [plasma membrane] (Mus musculus)
FGFR-1 homodimer [plasma membrane] (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P16092 Fgfr1
Gene Names
Fgfr1, Flg
Chain
signal peptide:1-21, chain:22-822
Reference Genes
BioGPS Gene:14182 Fgfr1
ENSEMBL:ENSMUSG00000031565 Fgfr1
KEGG Gene (Mus musculus):14182 Fgfr1
Monarch:14182 Fgfr1
NCBI Gene:14182 Fgfr1
UCSC:P16092 Fgfr1
Reference Transcript
RefSeq:NM_010206.3 Fgfr1
RefSeq:XM_006509012.1 Fgfr1
RefSeq:XM_011242121.1 Fgfr1
RefSeq:NM_001079908.2 Fgfr1
RefSeq:XM_006509010.2 Fgfr1
RefSeq:NM_001079909.2 Fgfr1
Other Identifiers
10570982
14182
1424050_s_at
1425911_a_at
1436551_at
17500108
4322453
4446912
4654147
4710897
4715504
4741317
4755293
4770585
4777523
4779741
4969419
4999827
5019455
5202052
5210884
5228863
5261908
5332521
5391172
5414655
5444292
5463968
5466199
5585364
5587337
5597520
97509_f_at
A_52_P136162
A_52_P552062
A_52_P668810
A_55_P1967015
A_55_P1967022
A_55_P2057777
GE35402
GO:0000122
GO:0000166
GO:0000278
GO:0001525
GO:0001657
GO:0001701
GO:0001759
GO:0001837
GO:0002053
GO:0002062
GO:0003674
GO:0004672
GO:0004713
GO:0004714
GO:0005007
GO:0005102
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005887
GO:0006464
GO:0006468
GO:0006629
GO:0006810
GO:0006950
GO:0007049
GO:0007165
GO:0007169
GO:0007267
GO:0007275
GO:0007420
GO:0007435
GO:0007605
GO:0008150
GO:0008201
GO:0008219
GO:0008283
GO:0008284
GO:0008543
GO:0009058
GO:0009790
GO:0010468
GO:0010629
GO:0010763
GO:0010863
GO:0010966
GO:0010976
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016740
GO:0017134
GO:0018108
GO:0019827
GO:0021700
GO:0021769
GO:0021837
GO:0021847
GO:0021954
GO:0030154
GO:0030324
GO:0030326
GO:0030901
GO:0031175
GO:0031410
GO:0032991
GO:0033674
GO:0034641
GO:0035607
GO:0040007
GO:0040011
GO:0042127
GO:0042169
GO:0042472
GO:0042473
GO:0042474
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0043235
GO:0043406
GO:0043410
GO:0043536
GO:0043583
GO:0044281
GO:0044877
GO:0045597
GO:0045666
GO:0045668
GO:0045787
GO:0045944
GO:0046777
GO:0048339
GO:0048378
GO:0048469
GO:0048471
GO:0048514
GO:0048646
GO:0048699
GO:0048762
GO:0048856
GO:0048870
GO:0050729
GO:0050839
GO:0050877
GO:0051174
GO:0051301
GO:0051897
GO:0051930
GO:0060045
GO:0060117
GO:0060445
GO:0060484
GO:0060665
GO:0060979
GO:0070640
GO:0072091
GO:0090080
GO:0090272
GO:0090722
GO:1903465
GO:1905564
GO:2000491
GO:2000546
GO:2000830
GO:2001239
ILMN_2675581
ILMN_2727068
m33760_s_at
mMC019594
Participant Of
input
FGFR1c binds to FGF
FGFR1c binds to Klotho-bound FGF23
L1-FGFR cis-heterodimerization
hasComponent
FGFR-1 homodimer [plasma membrane]
L1:FGFR1 [plasma membrane]
Other forms of this molecule
phospho-Fgfr1 [plasma membrane]
phospho-Fgfr1 [plasma membrane]
Fgfr1 [plasma membrane]
Inferred From
FGFR1c [plasma membrane] (Homo sapiens)
Cross References
RefSeq
NP_034336.2
,
XP_006509075.1
,
NP_001073378.1
,
XP_006509073.1
,
XP_011240423.1
,
NP_001073377.1
ZINC - Substances
FGFR1_MOUSE
ZINC target
P16092
Ensembl
ENSMUST00000119398
,
ENSMUST00000117179
,
ENSMUSP00000113909
,
ENSMUSP00000113855
,
ENSMUSP00000131343
,
ENSMUST00000178276
,
ENSMUST00000084027
,
ENSMUSG00000031565
,
ENSMUSP00000137515
,
ENSMUSP00000081041
,
ENSMUST00000167764
PRO
P16092
MGI
95522
ZINC - Predictions - Purchasable
FGFR1_MOUSE
PDB
2CKN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99N32
1
Klb [plasma membrane]
(R-MMU-1307932)
0.576
3
UniProt:O35082
2
Kl [extracellular region]
(R-MMU-190201)
Kl [plasma membrane]
(R-MMU-190198)
0.499
2
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