Reactome | Cxcl3 [extracellular region]

Cxcl3 [extracellular region]

Stable Identifier

R-MMU-373777-2

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

CXCL2(35-107), Q6W5C0

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Chemokine receptors bind chemokines (Mus musculus)
        
        Receptor CXCR2 binds ligands CXCL1 to 7 (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Mus musculus)
        
        CXCR2 ligands [extracellular region] (Mus musculus)
        
        Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)
        
        Cxcl3 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q6W5C0

Gene Names

Cxcl3

Reference Genes

BioGPS Gene:330122 Cxcl3

ENSEMBL:ENSMUSG00000029379

KEGG:mmu:330122 Cxcl3

Monarch:330122 Cxcl3

NCBI Gene:330122 Cxcl3

UCSC:Q6W5C0 Cxcl3

Reference Transcript

RefSeq:NM_203320.3 Cxcl3

Other Identifiers

10523138

1438148_at

17438975

330122

4351658

4423443

4608904

4766551

4857108

4954779

5003511

5210911

5215170

5238542

5345963

5382073

5440871

5536857

5603360

A_52_P232813

GE1530229

GO:0002376

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0006935

GO:0006952

GO:0006954

GO:0006955

GO:0007165

GO:0007204

GO:0008009

GO:0030593

GO:0032496

GO:0048018

GO:0048870

GO:0071222

GO:0098772

ILMN_2709267

mMC020440

Participates

as a member of

Homologues of CXCL2(35-107) [extracellular region] (Mus musculus)

Inferred From

CXCL3(35-107) [extracellular region] (Homo sapiens)

CXCL2(35-107) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_976065.1

ENSEMBL

ENSMUST00000031326, ENSMUSP00000031326, ENSMUSG00000029379

PRO

Q6W5C0

MGI

3037818

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