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phospho-Plcg2 [plasma membrane]
Stable Identifier
R-MMU-2685601
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
p-4Y-PLCG2, Q8CIH5
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
DAP12 interactions (Mus musculus)
DAP12 signaling (Mus musculus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Mus musculus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:p-PLCG [plasma membrane] (Mus musculus)
p-4Y-PLCG [plasma membrane] (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
Release of p-PLCG1 (Mus musculus)
p-4Y-PLCG [plasma membrane] (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:p-PLCG [plasma membrane] (Mus musculus)
p-4Y-PLCG [plasma membrane] (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated Ca+2 mobilization (Mus musculus)
Hydrolysis of PIP2 by PLCG (Mus musculus)
p-4Y-PLCG [plasma membrane] (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Mus musculus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:p-PLCG [plasma membrane] (Mus musculus)
p-4Y-PLCG [plasma membrane] (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8CIH5 Plcg2
Gene Names
Plcg2
Chain
chain:1-1265
Reference Genes
BioGPS Gene:234779 Plcg2
ENSEMBL:ENSMUSG00000034330.11 Plcg2
KEGG Gene (Mus musculus):234779 Plcg2
Monarch:234779 Plcg2
NCBI Gene:234779 Plcg2
UCSC:Q8CIH5 Plcg2
Reference Transcript
RefSeq:NM_172285.2 Plcg2
Other Identifiers
103503_at
10575799
1426926_at
17505995
234779
4316765
4328643
4347247
4418921
4464023
4513213
4544728
4546585
4561863
4688301
4698350
4706243
4722083
4757740
4778254
4794214
4839532
4844036
4845341
4893048
4914276
4922360
4930594
4951069
5054246
5125785
5150133
5172364
5188123
5197415
5235706
5254217
5381157
5396840
5400208
5436845
5465325
5476990
5598465
GE113622
GO:0001775
GO:0001784
GO:0001878
GO:0002092
GO:0002223
GO:0002224
GO:0002281
GO:0002316
GO:0002376
GO:0002732
GO:0003824
GO:0004435
GO:0004629
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006629
GO:0006661
GO:0006954
GO:0007165
GO:0007204
GO:0008081
GO:0009395
GO:0010468
GO:0010628
GO:0010634
GO:0012501
GO:0016020
GO:0016042
GO:0016192
GO:0016787
GO:0019216
GO:0019722
GO:0019901
GO:0023052
GO:0030154
GO:0030183
GO:0031663
GO:0032026
GO:0032481
GO:0032496
GO:0032587
GO:0032733
GO:0032735
GO:0032743
GO:0032747
GO:0032755
GO:0032760
GO:0032959
GO:0033198
GO:0034480
GO:0035556
GO:0036211
GO:0043069
GO:0043122
GO:0043226
GO:0043410
GO:0045121
GO:0048015
GO:0048471
GO:0048678
GO:0048856
GO:0048870
GO:0050731
GO:0050850
GO:0050852
GO:0050853
GO:0050896
GO:0051091
GO:0051092
GO:0051209
GO:0055065
GO:0055085
GO:0060100
GO:0060907
GO:0061024
GO:0061760
GO:0065003
GO:0070884
GO:0071277
GO:0071396
GO:0097110
GO:0097708
GO:0098542
GO:0140031
GO:0150078
GO:1900227
GO:1902808
GO:1903428
GO:1903721
GO:1990782
GO:1990858
ILMN_2601833
c76245_rc_at
mMC012791
Participates
as a member of
p-4Y-PLCG [plasma membrane] (Mus musculus)
Other forms of this molecule
p-Y-Plcg2 [cytosol]
Plcg2 [cytosol]
phospho-Plcg2 [cytosol]
phospho-Plcg2 [plasma membrane]
p-Y753,Y759-Plcg2 [cytosol]
phospho-Plcg2 [plasma membrane]
Plcg2 [plasma membrane]
phospho-Plcg2 [plasma membrane]
Inferred From
p-4Y-PLCG2 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 753 (in Homo sapiens)
Coordinate
753
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 759 (in Homo sapiens)
Coordinate
759
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1217 (in Homo sapiens)
Coordinate
1217
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1197 (in Homo sapiens)
Coordinate
1197
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_758489.1
IntEnz
3.1.4.11
Ensembl
ENSMUST00000081232
,
ENSMUSP00000079991
,
ENSMUSG00000034330
PRO
Q8CIH5
MGI
97616
PDB
2DX0
,
2EQI
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25911 Lyn
7
MyrG2-PalmC3-LYN [lysosomal membrane]
(R-MMU-9707903)
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
(R-MMU-9705728)
LYN [plasma membrane]
(R-MMU-197943)
phospho-p-Y397-LYN [cytosol]
(R-MMU-8942608)
phospho-p-Y397-LYN [plasma membrane]
(R-MMU-2454229)
MyrG2-PalmC3-LYN [plasma membrane]
(R-MMU-9606875)
Lyn [cytosol]
(R-MMU-1112642)
0.524
2
UniProt:P14753 Epor
4
p-8Y-Epor [plasma membrane]
(R-MMU-9006275)
EpoR [plasma membrane]
(R-MMU-206154)
Epor [plasma membrane]
(R-MMU-1168347)
phospho-Epor [plasma membrane]
(R-MMU-9006274)
0.524
2
UniProt:P07333 CSF1R
4
PolyUb,p-8Y-CSF1R [plasma membrane]
(R-HSA-389142)
PolyUb,p-Y561-CSF1R [plasma membrane]
(R-HSA-9733335)
p-Y561-CSF1R [plasma membrane]
(R-HSA-9733328)
CSF1R [plasma membrane]
(R-HSA-197667)
0.482
2
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