Reactome | Numb [plasma membrane]

Numb [plasma membrane]

Stable Identifier

R-MMU-2077469

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

External Reference Information

External Reference

UniProt:Q9QZS3 Numb

Gene Names

Numb

Chain

chain:1-653

Reference Genes

BioGPS Gene:18222 NUMB

KEGG:mmu:18222 NUMB

Monarch:18222 NUMB

NCBI Gene:18222 NUMB

UCSC:Q9QZS3 NUMB

Reference Transcript

Participates

as a component of

Notch1:Numb:Itch [plasma membrane] (Mus musculus)

as an input of

Numb recruits Itch to Notch1 (Mus musculus)

Other forms of this molecule

Numb [plasma membrane]

Cross References

RefSeq

XP_006515641.1, XP_011242314.1, NP_001258985.1, XP_006515640.1, NP_001398881.1, NP_001258984.1, NP_035079.1, NP_001398880.1, XP_006515639.1, NP_001129547.1, NP_001398879.1, NP_001398878.1

ENSEMBL

ENSMUST00000154043, ENSMUSP00000113591, ENSMUSG00000021224, ENSMUSP00000117899, ENSMUSP00000021647, ENSMUSP00000119303, ENSMUST00000117217, ENSMUST00000021647, ENSMUST00000129335

PRO

Q9QZS3

MGI

107423

PDB

1WJ1, 5YQG

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05106 ITGB3	3	ITGB3 [plasma membrane] (R-HSA-57600) ITGB3(27-?) [platelet alpha granule membrane] (R-HSA-114512) p-T779-ITGB3 [plasma membrane] (R-HSA-432107)	0.544	2
UniProt:P12023	11	App [extracellular region] (R-MMU-879340) App [extracellular region] (R-MMU-976740) App [platelet alpha granule lumen] (R-MMU-139835) App [extracellular region] (R-MMU-49335) App [endoplasmic reticulum lumen] (R-MMU-8956696) phospho-App [endoplasmic reticulum lumen] (R-MMU-8957012) App [endosome lumen] (R-MMU-5229077) App [mitochondrial inner membrane] (R-MMU-9839060) App [cytosol] (R-MMU-9839084) App [cytosol] (R-MMU-9617603) App [trans-Golgi network membrane] (R-MMU-5229136)	0.471	2

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