Reactome | DNAJC10 [endoplasmic reticulum lumen]

DNAJC10 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-9920089

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Locations in the PathwayBrowser for interactor UniProt:P00533 EGFR

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External Reference Information

External Reference

UniProt:Q8IXB1 DNAJC10

Gene Names

DNAJC10, ERDJ5, UNQ495/PRO1012

Chain

signal peptide:1-32, chain:33-793

Reference Genes

BioGPS Gene:54431 DNAJC10

COSMIC - genes:DNAJC10 DNAJC10

CTD Gene:54431 DNAJC10

dbSNP Gene:54431 DNAJC10

ENSEMBL:ENSG00000077232 DNAJC10

HGNC:24637 DNAJC10

KEGG:hsa:54431 DNAJC10

Monarch:54431 DNAJC10

NCBI Gene:54431 DNAJC10

OMIM:607987 DNAJC10

UCSC:Q8IXB1 DNAJC10

Reference Transcript

Other Identifiers

11720045_a_at

11720046_x_at

11744578_s_at

11752102_s_at

11758820_at

11760218_a_at

11764170_at

16888367

221781_PM_s_at

221781_s_at

221782_PM_at

221782_at

225174_PM_at

225174_at

229588_3p_at

229588_PM_at

229588_at

243635_PM_at

243635_at

2518593

2518594

2518595

2518598

2518599

2518600

2518601

2518602

2518604

2518605

2518606

2518607

2518609

2518611

2518612

2518613

2518614

2518615

2518616

2518617

2518618

2518619

2518620

2518621

2518622

2518623

2518624

2518625

2518627

2518628

2518629

2518630

2518631

2518636

2518639

2518643

2518644

2518645

2518646

2518647

2518648

2518649

2518650

2518651

2518652

2518653

2518654

2518655

2518656

2518658

2518659

2518660

2518662

2518664

2518666

2518668

46779_r_at

46817_at

48849_i_at

48850_r_at

51927_at

52343_s_at

54431

54808_at

58797_at

8046759

A_14_P131825

A_14_P138802

A_19_P00809259

A_23_P319133

A_24_P217063

A_24_P225604

GE56768

GE891923

GE903954

GO:0001671

GO:0003824

GO:0005515

GO:0005783

GO:0005788

GO:0015035

GO:0015036

GO:0016020

GO:0016491

GO:0016671

GO:0030163

GO:0030544

GO:0034663

GO:0034975

GO:0034976

GO:0036498

GO:0036503

GO:0051087

GO:0051117

GO:0051787

GO:0070059

GO:0098772

GO:0140096

HMNXSV003031082

Hs.1098.0.A1_3p_at

Hs.1098.0.A1_3p_s_at

Hs.1098.0.A2_3p_at

Hs.46669.0.A1_3p_at

Hs.69165.0.A1_3p_at

Hs.69165.0.A1_3p_x_at

ILMN_1656486

ILMN_2151541

PH_hs_0000143

TC02001089.hg

This entity regulates

Positively

HyPro-polyprotein folds (Homo sapiens)

Cross References

RefSeq

NP_001258510.1, NP_061854.1

ENSEMBL

ENST00000264065, ENST00000616986, ENST00000680480, ENSP00000479930, ENSP00000441560, ENSP00000264065, ENST00000537515, ENSG00000077232, ENSP00000505358

OpenTargets

ENSG00000077232

IntEnz

1.8.4.2

GeneCards

DNAJC10

HPA

ENSG00000077232-DNAJC10

PRO

Q8IXB1

Pharos - Targets

Q8IXB1

GlyGen

Q8IXB1

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.643	3
UniProt:P28290 ITPI2			0.527	2
UniProt:Q5VU43 MYOME			0.527	2
UniProt:P55268 LAMB2	3	LAMB2 [extracellular region] (R-HSA-215961) p-LAMB2 [endoplasmic reticulum lumen] (R-HSA-8957053) LAMB2 [endoplasmic reticulum lumen] (R-HSA-8956752)	0.527	2
UniProt:Q9NZR2 LRP1B			0.527	2
UniProt:Q9UM47 NOTCH3	20	Ub-NICD3 [cytosol] (R-HSA-9021546) Ub-NEXT3 [plasma membrane] (R-HSA-9021545) p-Y-NICD3 [cytosol] (R-HSA-9018581) Glc,GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane] (R-HSA-1911429) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane] (R-HSA-1911419) NOTCH3(1572-2321) [Golgi membrane] (R-HSA-156995) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [Golgi membrane] (R-HSA-1983672) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [extracellular region] (R-HSA-1983675) NOTCH3(1572-2321) [plasma membrane] (R-HSA-157231) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [Golgi membrane] (R-HSA-1472871) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane] (R-HSA-1467307) 10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane] (R-HSA-1467382) Pre-NOTCH3 [endoplasmic reticulum membrane] (R-HSA-157102) NICD3 [nucleoplasm] (R-HSA-157928) NICD3 [cytosol] (R-HSA-157647) NEXT3 [plasma membrane] (R-HSA-157203) NOTCH3(1629-1661) [plasma membrane] (R-HSA-157657) NOTCH3(40-1628) [extracellular region] (R-HSA-157639) FRINGE-modified NOTCH3 Extracellular fragment (NECD3) [Golgi membrane] (R-HSA-1911522) FRINGE-modified NOTCH3 Extracellular Fragment (NECD3) [plasma membrane] (R-HSA-1911517)	0.527	2
UniProt:Q9UBX5 FBLN5	1	FBLN5 [extracellular region] (R-HSA-2161278)	0.527	2
UniProt:Q9NYA4 MTMR4	2	MTMR4 [cytosol] (R-HSA-1604658) MTMR4 [early endosome membrane] (R-HSA-2187404)	0.527	2
UniProt:P00533 EGFR	20	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334)	0.483	3

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