Reactome | SYTL2 [cytosol]

SYTL2 [cytosol]

Stable Identifier

R-HSA-9856433

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Synaptotagmin-like protein 2, SYTL2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HCH5 SYTL2

Gene Names

SYTL2, KIAA1597, SGA72M, SLP2, SLP2A

Chain

chain:1-934

Reference Genes

BioGPS Gene:54843 SYTL2

COSMIC (genes):SYTL2 SYTL2

CTD Gene:54843 SYTL2

dbSNP Gene:54843 SYTL2

ENSEMBL:ENSG00000137501 SYTL2

HGNC:15585 SYTL2

KEGG:hsa:54843 SYTL2

Monarch:54843 SYTL2

NCBI Gene:54843 SYTL2

OMIM:612880 SYTL2

UCSC:Q9HCH5 SYTL2

Reference Transcript

Participates

as a component of

GGC-RAB27A:MLPH,MYRIP:SYTL2:p-S1652-MYO5A dimer [melanosome membrane] (Homo sapiens)

as an input of

MLPH/MYRIP bind GGC-RAB27A and MYO5A (Homo sapiens)

Inferred To

Sytl2 [cytosol] (Mus musculus)

Sytl2 [cytosol] (Rattus norvegicus)

SYTL2 [cytosol] (Bos taurus)

SYTL2 [cytosol] (Canis familiaris)

SYTL2 [cytosol] (Gallus gallus)

Cross References

OpenTargets

ENSG00000137501

ENSEMBL

ENST00000389960, ENSP00000318803, ENSP00000431701, ENST00000529581, ENSP00000374608, ENST00000316356, ENST00000533892, ENST00000527523, ENST00000524452, ENST00000528231, ENST00000525702, ENSG00000137501, ENSP00000434010, ENST00000389958, ENSP00000435855, ENSP00000432144, ENSP00000374610, ENSP00000435238, ENSP00000432996

HPA

ENSG00000137501-SYTL2

GeneCards

SYTL2

PRO

Q9HCH5

Pharos - Targets

Q9HCH5

GlyGen

Q9HCH5

PDB

3BC1, 7OPP, 7OPR, 7OPQ

HMDB Protein

HMDBP08591

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9ERI2	5	GGC-RAB27A [cytosol] (R-MMU-8870427) RAB27A [cytosol] (R-MMU-3008674) GGC-RAB27A [melanosome membrane] (R-MMU-8877281) RAB27A [extracellular region] (R-MMU-6799682) RAB27A [specific granule lumen] (R-MMU-6799609)	0.618	4
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.592	2

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