Reactome | GGC-RAB27A [cytosol]

GGC-RAB27A [cytosol]

Stable Identifier

R-MMU-8870427

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q9ERI2

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - Rab regulation of trafficking (Mus musculus)
    - RAB GEFs exchange GTP for GDP on RABs (Mus musculus)
      - MADD exchanges GTP for GDP on RAB27 (Mus musculus)
        
        GGC-RAB27:GDP:GDIs,CHMs [cytosol] (Mus musculus)
        
        RAB27:GDP [cytosol] (Mus musculus)
        
        GGC-RAB27A:GDP [cytosol] (Mus musculus)
        
        GGC-RAB27A [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9ERI2

Reference Genes

BioGPS Gene:11891

ENSEMBL:ENSMUSG00000032202

KEGG:mmu:11891

Monarch:11891

NCBI Gene:11891

UCSC:Q9ERI2

Reference Transcript

Other Identifiers

10587023

11891

1425284_a_at

1425285_a_at

1429123_at

163478_at

17519282

4313174

4321660

4330689

4334318

4423392

4485691

4520506

4654393

4827166

4904264

4996309

5049448

5078696

5136212

5183138

5398771

5460478

5484980

A_52_P29615

A_52_P426740

GE40540

GO:0000166

GO:0001750

GO:0002376

GO:0003924

GO:0003925

GO:0005515

GO:0005525

GO:0005737

GO:0005764

GO:0005768

GO:0005770

GO:0005794

GO:0006887

GO:0007596

GO:0009306

GO:0010628

GO:0012505

GO:0016020

GO:0016192

GO:0016324

GO:0016787

GO:0019003

GO:0019882

GO:0019904

GO:0030141

GO:0030154

GO:0030318

GO:0030425

GO:0031410

GO:0031489

GO:0032400

GO:0032402

GO:0032585

GO:0033093

GO:0036257

GO:0042470

GO:0043316

GO:0043320

GO:0043473

GO:0045921

GO:0050766

GO:0051875

GO:0051904

GO:0070382

GO:0071985

GO:0097278

GO:0098772

GO:1903307

GO:1903428

GO:1903435

GO:1990182

ILMN_2614966

mMC008005

Participates

as a component of

GGC-RAB27A:GDP [cytosol] (Mus musculus)

as a candidate of

GGC-RABs [cytosol] (Mus musculus)

Other forms of this molecule

RAB27A [cytosol]

GGC-RAB27A [melanosome membrane]

RAB27A [extracellular region]

RAB27A [specific granule lumen]

Inferred From

GGC-RAB27A [cytosol] (Homo sapiens)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 219 (in Homo sapiens)

Coordinate

219

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 221 (in Homo sapiens)

Coordinate

221

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

NP_001288161.1, XP_006510843.1, NP_076124.1, NP_001288159.1

ENSEMBL

ENSMUST00000034722, ENSMUST00000184146, ENSMUSG00000032202, ENSMUSP00000034722, ENSMUSP00000139310

IntEnz

3.6.5.2

PRO

Q9ERI2

MGI

1861441

PDB

3BC1

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9HCH5 SYTL2	1	SYTL2 [cytosol] (R-HSA-9856433)	0.618	4
UniProt:Q91V27	1	Mlph [cytosol] (R-MMU-9856432)	0.589	2
UniProt:P47708 RP3A			0.589	2
UniProt:Q8TDW5 SYTL5			0.544	2
UniProt:Q99P58	5	GGC-RAB27B [melanosome membrane] (R-MMU-8877280) GGC-RAB27B [cytosol] (R-MMU-8873786) RAB27B [cytosol] (R-MMU-8873706) RAB27B [plasma membrane] (R-MMU-8862952) RAB27B [platelet dense granule membrane] (R-MMU-8862955)	0.482	3