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Ag-substrate:E3:E2:Ub [cytosol]
Stable Identifier
R-HSA-983126
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Participants
components
antigenic substrate [cytosol]
E3 ligases in proteasomal degradation [cytosol]
(Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol]
(Homo sapiens)
Participates
as an output of
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
as an input of
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Inferred To
Ag-substrate:E3:E2:Ub [cytosol]
(Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol]
(Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol]
(Canis familiaris)
Ag-substrate:E3:E2:Ub [cytosol]
(Danio rerio)
Ag-substrate:E3:E2:Ub [cytosol]
(Dictyostelium discoideum)
Ag-substrate:E3:E2:Ub [cytosol]
(Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol]
(Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol]
(Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol]
(Plasmodium falciparum)
Ag-substrate:E3:E2:Ub [cytosol]
(Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol]
(Saccharomyces cerevisiae)
Ag-substrate:E3:E2:Ub [cytosol]
(Schizosaccharomyces pombe)
Ag-substrate:E3:E2:Ub [cytosol]
(Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol]
(Xenopus tropicalis)
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