Complement factor I complex formation

Stable Identifier
R-HSA-976801
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Complement factor I (CFI) is a complex of one heavy and one light chain, both cleaved from the same precursor peptide. It inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage of the alpha chains of C4b and C3b in the presence of cofactors such as Factor H, C4b binding protein, Complement receptor 1 (CR1) or MCP (CD46).

Literature References
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Orthologous Events
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Created