Regulation of CDH1 mRNA translation by microRNAs

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R-HSA-9764562
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Homo sapiens
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3/5
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Regulation of CDH1 mRNA translation by microRNAs
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Regulation of CDH1 mRNA translation by microRNAs has not been extensively characterized. So far, miR-9 (miR-9-1, miR-9-2, and miR-9-3) microRNAs (Ma et al. 2010; Liu et al. 2013; Drakaki et al. 2015; Nishioka et al. 2017), whose expression is regulated by MYC/MYCN (Ma et al. 2010; Liu et al. 2013; DA Silva Oliveira et al. 2017; Qin et al. 2022), and miR-10b (Ma et al. 2010; Zhang et al. 2015; Ma et al. 2017) were reported to directly regulate CDH1 mRNA translation by more than one study.

Other microRNAs implicated in the direct regulation of CDH1 microRNA expression by a single study include miR-23b (Wang et al. 2016), miR106a (Lin et al. 2020), miR-155 (Kline et al. 2020), and miR-503 (Zhao et al. 2017).

Literature References
PubMed ID Title Journal Year
28107581 MicroRNA-9 plays a role in interleukin-10-mediated expression of E-cadherin in acute myelogenous leukemia cells

Nishioka, C, Ikezoe, T, Pan, B, Xu, K, Yokoyama, A

Cancer Sci 2017
28476807 Expression of hsa-miR-9 and MYC Copy Number Variation in Hereditary Diffuse Gastric Cancer

DA Silva Oliveira, KC, Bona, AB, DA Silva, FJ, Pinheiro, TM, DI Felipe Avila Alcantara, D, Lamarao, LM, Moreira-Nunes, CA, Assumpcao, PP, Burbano, RR, Calcagno, DQ

Anticancer Res 2017
32714095 Circular RNA ITCH suppresses proliferation, invasion, and glycolysis of ovarian cancer cells by up-regulating CDH1 via sponging miR-106a

Lin, C, Xu, X, Yang, Q, Liang, L, Qiao, S

Cancer Cell Int 2020
25875782 MicroRNA-10b Triggers the Epithelial-Mesenchymal Transition (EMT) of Laryngeal Carcinoma Hep-2 Cells by Directly Targeting the E-cadherin

Zhang, L, Sun, J, Wang, B, Ren, JC, Su, W, Zhang, T

Appl Biochem Biotechnol 2015
26206264 Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

Drakaki, A, Hatziapostolou, M, Polytarchou, C, Vorvis, C, Poultsides, GA, Souglakos, J, Georgoulias, V, Iliopoulos, D

BMC Cancer 2015
28393237 MicroRNA-10b mediates TGF-β1-regulated glioblastoma proliferation, migration and epithelial-mesenchymal transition

Ma, C, Wei, F, Xia, H, Liu, H, Dong, X, Zhang, Y, Luo, Q, Liu, Y, Li, Y

Int J Oncol 2017
23364919 c-Myc suppressed E-cadherin through miR-9 at the post-transcriptional level

Liu, M, Zhu, H, Yang, S, Wang, Z, Bai, J, Xu, N

Cell Biol Int 2013
28161325 miR-503-3p promotes epithelial-mesenchymal transition in breast cancer by directly targeting SMAD2 and E-cadherin

Zhao, Z, Fan, X, Jiang, L, Xu, Z, Xue, L, Zhan, Q, Song, Y

J Genet Genomics 2017
31889022 Neonatal Injury Increases Gut Permeability by Epigenetically Suppressing E-Cadherin in Adulthood

Kline, KT, Lian, H, Zhong, XS, Luo, X, Winston, JH, Cong, Y, Savidge, TC, Dashwood, RH, Powell, DW, Li, Q

J Immunol 2020
27150436 MicroRNA-23b regulates nasopharyngeal carcinoma cell proliferation and metastasis by targeting E-cadherin

Wang, JY, Li, XF, Li, PZ, Zhang, X, Xu, Y, Jin, X

Mol Med Rep 2016
35122989 C-MYC induces idiopathic pulmonary fibrosis via modulation of miR-9-5p-mediated TBPL1

Qin, H, Tang, Y, Mao, Y, Zhou, X, Xu, T, Liu, W, Su, X

Cell Signal 2022
20173740 miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

Ma, L, Young, J, Prabhala, H, Pan, E, Mestdagh, P, Muth, D, Teruya-Feldstein, J, Reinhardt, F, Onder, TT, Valastyan, S, Westermann, F, Speleman, F, Vandesompele, J, Weinberg, RA

Nat Cell Biol 2010
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Orlic-Milacic, M  (2022-02-11)
Created
Orlic-Milacic, M  (2022-02-11)
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