miR-10b binds CDH1 mRNA

Stable Identifier
R-HSA-9768643
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
3/5
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miR-10b binds CDH1 mRNA
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A single miR-10b target site was computationally predicted in the CDH1 mRNA 3′-UTR and its direct targeting was demonstrated by a luciferase assay in which a wild-type or a mutant CDH1 mRNA 3'UTR was fused to the luciferase gene (Zhang et al. 2015) and a luciferase assay in which a wild-type miR-10b or a mutant miR-10b was used (Ma et al. 2017).
Literature References
PubMed ID Title Journal Year
25875782 MicroRNA-10b Triggers the Epithelial-Mesenchymal Transition (EMT) of Laryngeal Carcinoma Hep-2 Cells by Directly Targeting the E-cadherin

Zhang, L, Sun, J, Wang, B, Ren, JC, Su, W, Zhang, T

Appl Biochem Biotechnol 2015
28393237 MicroRNA-10b mediates TGF-β1-regulated glioblastoma proliferation, migration and epithelial-mesenchymal transition

Ma, C, Wei, F, Xia, H, Liu, H, Dong, X, Zhang, Y, Luo, Q, Liu, Y, Li, Y

Int J Oncol 2017
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Authored
Orlic-Milacic, M  (2022-03-14)
Created
Orlic-Milacic, M  (2022-03-14)
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